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Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process
Tetrahedron Letters
Swansea University Author:
Leo Prakash
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DOI (Published version): 10.1016/j.tetlet.2014.02.086
Abstract
It is aimed to provide a cost effective p-NBSA catalyzed nucleophilic substitution of propargyl alcohols with alcohols, amines and heterocycles, without employing corrosive and costly metal catalysts, toxic solvents and column chromatography for purification. A systematic study of C-C, C-N and C-O b...
Published in: | Tetrahedron Letters |
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2014
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URI: | https://cronfa.swan.ac.uk/Record/cronfa17634 |
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2018-09-13T14:32:45.4120964 v2 17634 2014-04-01 Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process bd72868c48af6c0b04bf9f6bb48ce324 0000-0002-8812-8927 Leo Prakash Leo Prakash true false 2014-04-01 MTLS It is aimed to provide a cost effective p-NBSA catalyzed nucleophilic substitution of propargyl alcohols with alcohols, amines and heterocycles, without employing corrosive and costly metal catalysts, toxic solvents and column chromatography for purification. A systematic study of C-C, C-N and C-O bond formation and efficacy of the scalability have also been confirmed. Journal Article Tetrahedron Letters Propargyl alcohol; Propargyl ether; Propargyl amine; Heterocycles; Sulfonic acids 21 5 2014 2014-05-21 10.1016/j.tetlet.2014.02.086 COLLEGE NANME Materials Science and Engineering COLLEGE CODE MTLS Swansea University 2018-09-13T14:32:45.4120964 2014-04-01T10:03:49.1835072 Faculty of Science and Engineering School of Engineering and Applied Sciences - Materials Science and Engineering S. Antony Savarimuthu 1 D.G. Leo Prakash 2 S. Augustine Thomas 3 Leo Prakash 0000-0002-8812-8927 4 |
title |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process |
spellingShingle |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process Leo Prakash |
title_short |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process |
title_full |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process |
title_fullStr |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process |
title_full_unstemmed |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process |
title_sort |
Nucleophilic substitution of propargyl alcohols with aliphatic alcohols, aliphatic amines and heterocycles catalyzed by 4-nitrobenzenesulfonic acid: A scalable and metal-free process |
author_id_str_mv |
bd72868c48af6c0b04bf9f6bb48ce324 |
author_id_fullname_str_mv |
bd72868c48af6c0b04bf9f6bb48ce324_***_Leo Prakash |
author |
Leo Prakash |
author2 |
S. Antony Savarimuthu D.G. Leo Prakash S. Augustine Thomas Leo Prakash |
format |
Journal article |
container_title |
Tetrahedron Letters |
publishDate |
2014 |
institution |
Swansea University |
doi_str_mv |
10.1016/j.tetlet.2014.02.086 |
college_str |
Faculty of Science and Engineering |
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facultyofscienceandengineering |
hierarchy_top_title |
Faculty of Science and Engineering |
hierarchy_parent_id |
facultyofscienceandengineering |
hierarchy_parent_title |
Faculty of Science and Engineering |
department_str |
School of Engineering and Applied Sciences - Materials Science and Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Materials Science and Engineering |
document_store_str |
0 |
active_str |
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description |
It is aimed to provide a cost effective p-NBSA catalyzed nucleophilic substitution of propargyl alcohols with alcohols, amines and heterocycles, without employing corrosive and costly metal catalysts, toxic solvents and column chromatography for purification. A systematic study of C-C, C-N and C-O bond formation and efficacy of the scalability have also been confirmed. |
published_date |
2014-05-21T03:20:24Z |
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1763750576096542720 |
score |
10.970258 |