Journal article 1289 views
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
E.V. Grizanova,
I.M. Dubovskiy,
M.M.A. Whitten,
V.V. Glupov,
Miranda Walker
Journal of Invertebrate Pathology, Volume: 119, Pages: 40 - 46
Swansea University Author: Miranda Walker
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DOI (Published version): 10.1016/j.jip.2014.04.003
Abstract
The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it...
| Published in: | Journal of Invertebrate Pathology |
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| Published: |
2014
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa17945 |
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| Abstract: |
The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it elicits insect killing via a combination of toxin production, dysbiosis and / or septicaemia. However, the nature of the immune & stress responses triggered in host insects has not yet been fully evaluated, nor has the nature of possible resistance or tolerance mechanisms. This paper addresses these issues, and proposes possible tolerance mechanisms that will help inform future biocontrol strategies. |
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| Keywords: |
biocontrol, insect, Bacillus thuringiensis, immunology |
| College: |
Faculty of Medicine, Health and Life Sciences |
| Start Page: |
40 |
| End Page: |
46 |