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Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis

E.V. Grizanova, I.M. Dubovskiy, M.M.A. Whitten, V.V. Glupov, Miranda Walker

Journal of Invertebrate Pathology, Volume: 119, Pages: 40 - 46

Swansea University Author: Miranda Walker

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DOI (Published version): 10.1016/j.jip.2014.04.003

Abstract

The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it...

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Published in: Journal of Invertebrate Pathology
Published: 2014
URI: https://cronfa.swan.ac.uk/Record/cronfa17945
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first_indexed 2014-05-13T01:30:02Z
last_indexed 2018-02-09T04:52:03Z
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spelling 2016-06-14T17:40:02.9903601 v2 17945 2014-05-12 Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis 83389c57d000a704fae36fda87d7ca76 Miranda Walker Miranda Walker true false 2014-05-12 FGMHL The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it elicits insect killing via a combination of toxin production, dysbiosis and / or septicaemia. However, the nature of the immune & stress responses triggered in host insects has not yet been fully evaluated, nor has the nature of possible resistance or tolerance mechanisms. This paper addresses these issues, and proposes possible tolerance mechanisms that will help inform future biocontrol strategies. Journal Article Journal of Invertebrate Pathology 119 40 46 biocontrol, insect, Bacillus thuringiensis, immunology 13 4 2014 2014-04-13 10.1016/j.jip.2014.04.003 COLLEGE NANME Medicine, Health and Life Science - Faculty COLLEGE CODE FGMHL Swansea University 2016-06-14T17:40:02.9903601 2014-05-12T13:53:38.3833753 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine E.V. Grizanova 1 I.M. Dubovskiy 2 M.M.A. Whitten 3 V.V. Glupov 4 Miranda Walker 5
title Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
spellingShingle Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
Miranda Walker
title_short Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
title_full Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
title_fullStr Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
title_full_unstemmed Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
title_sort Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
author_id_str_mv 83389c57d000a704fae36fda87d7ca76
author_id_fullname_str_mv 83389c57d000a704fae36fda87d7ca76_***_Miranda Walker
author Miranda Walker
author2 E.V. Grizanova
I.M. Dubovskiy
M.M.A. Whitten
V.V. Glupov
Miranda Walker
format Journal article
container_title Journal of Invertebrate Pathology
container_volume 119
container_start_page 40
publishDate 2014
institution Swansea University
doi_str_mv 10.1016/j.jip.2014.04.003
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it elicits insect killing via a combination of toxin production, dysbiosis and / or septicaemia. However, the nature of the immune & stress responses triggered in host insects has not yet been fully evaluated, nor has the nature of possible resistance or tolerance mechanisms. This paper addresses these issues, and proposes possible tolerance mechanisms that will help inform future biocontrol strategies.
published_date 2014-04-13T03:20:54Z
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score 11.012678

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