Journal article 1289 views
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis
Journal of Invertebrate Pathology, Volume: 119, Pages: 40 - 46
Swansea University Author: Miranda Walker (neeWhitten)
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DOI (Published version): 10.1016/j.jip.2014.04.003
Abstract
The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it...
Published in: | Journal of Invertebrate Pathology |
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2014
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URI: | https://cronfa.swan.ac.uk/Record/cronfa17945 |
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2018-02-09T04:52:03Z |
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2016-06-14T17:40:02.9903601 v2 17945 2014-05-12 Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis 83389c57d000a704fae36fda87d7ca76 0000-0003-1930-5042 Miranda Walker (neeWhitten) Miranda Walker (neeWhitten) true false 2014-05-12 MEDS The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it elicits insect killing via a combination of toxin production, dysbiosis and / or septicaemia. However, the nature of the immune & stress responses triggered in host insects has not yet been fully evaluated, nor has the nature of possible resistance or tolerance mechanisms. This paper addresses these issues, and proposes possible tolerance mechanisms that will help inform future biocontrol strategies. Journal Article Journal of Invertebrate Pathology 119 40 46 biocontrol, insect, Bacillus thuringiensis, immunology 13 4 2014 2014-04-13 10.1016/j.jip.2014.04.003 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2016-06-14T17:40:02.9903601 2014-05-12T13:53:38.3833753 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine E.V. Grizanova 1 I.M. Dubovskiy 2 M.M.A. Whitten 3 V.V. Glupov 4 Miranda Walker (neeWhitten) 0000-0003-1930-5042 5 |
title |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis |
spellingShingle |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis Miranda Walker (neeWhitten) |
title_short |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis |
title_full |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis |
title_fullStr |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis |
title_full_unstemmed |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis |
title_sort |
Contributions of cellular and humoral immunity of Galleria mellonella larvae in defence against oral infection by Bacillus thuringiensis |
author_id_str_mv |
83389c57d000a704fae36fda87d7ca76 |
author_id_fullname_str_mv |
83389c57d000a704fae36fda87d7ca76_***_Miranda Walker (neeWhitten) |
author |
Miranda Walker (neeWhitten) |
author2 |
E.V. Grizanova I.M. Dubovskiy M.M.A. Whitten V.V. Glupov Miranda Walker (neeWhitten) |
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Journal article |
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Journal of Invertebrate Pathology |
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119 |
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2014 |
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Swansea University |
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10.1016/j.jip.2014.04.003 |
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Faculty of Medicine, Health and Life Sciences |
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Faculty of Medicine, Health and Life Sciences |
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facultyofmedicinehealthandlifesciences |
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Faculty of Medicine, Health and Life Sciences |
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Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine |
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description |
The Greater wax moth Galleria mellonella was used as a model organism to elucidate the underlying mechanisms of host-pathogen interactions following challenge by the bacterial bio-pesticide Bacillus thuringiensis. This bacterium is a vital tool in integrated pest management and it is thought that it elicits insect killing via a combination of toxin production, dysbiosis and / or septicaemia. However, the nature of the immune & stress responses triggered in host insects has not yet been fully evaluated, nor has the nature of possible resistance or tolerance mechanisms. This paper addresses these issues, and proposes possible tolerance mechanisms that will help inform future biocontrol strategies. |
published_date |
2014-04-13T06:32:49Z |
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1821295530238541824 |
score |
11.231748 |