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Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock

Claire Hull, Joel Loveridge Orcid Logo, Nicola J Rolley, Iain S Donnison, Steven Kelly Orcid Logo, Diane Kelly

Biotechnology for Biofuels, Volume: 7, Issue: 1, Start page: 133

Swansea University Authors: Claire Hull, Joel Loveridge Orcid Logo, Steven Kelly Orcid Logo, Diane Kelly

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DOI (Published version): 10.1186/s13068-014-0133-7

Abstract

Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine habitats, sustainable sources of squalene are r...

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Published in: Biotechnology for Biofuels
Published: 2014
URI: https://cronfa.swan.ac.uk/Record/cronfa18617
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Abstract: Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine habitats, sustainable sources of squalene are required. This study investigated a microbial biorefinery approach to co-production of squalene and ethanol using an engineered strain of the yeast Saccharomyces cerevisiae.
College: Faculty of Medicine, Health and Life Sciences
Issue: 1
Start Page: 133