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Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock

Claire Hull, Joel Loveridge Orcid Logo, Nicola J Rolley, Iain S Donnison, Steven Kelly Orcid Logo, Diane Kelly

Biotechnology for Biofuels, Volume: 7, Issue: 1, Start page: 133

Swansea University Authors: Claire Hull, Joel Loveridge Orcid Logo, Steven Kelly Orcid Logo, Diane Kelly

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DOI (Published version): 10.1186/s13068-014-0133-7

Abstract

Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine habitats, sustainable sources of squalene are r...

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Published in: Biotechnology for Biofuels
Published: 2014
URI: https://cronfa.swan.ac.uk/Record/cronfa18617
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first_indexed 2014-10-07T01:58:15Z
last_indexed 2021-10-27T02:31:37Z
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spelling 2021-10-26T15:37:28.0047530 v2 18617 2014-10-06 Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock 6c495cb489b67bc9bb3f746975c4ff19 Claire Hull Claire Hull true false 5dd2760b388ec3cc2af33bb62f3f151a 0000-0002-8528-4019 Joel Loveridge Joel Loveridge true false b17cebaf09b4d737b9378a3581e3de93 0000-0001-7991-5040 Steven Kelly Steven Kelly true false 5ccf81e5d5beedf32ef8d7c3d7ac6c8c Diane Kelly Diane Kelly true false 2014-10-06 PMSC Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine habitats, sustainable sources of squalene are required. This study investigated a microbial biorefinery approach to co-production of squalene and ethanol using an engineered strain of the yeast Saccharomyces cerevisiae. Journal Article Biotechnology for Biofuels 7 1 133 31 10 2014 2014-10-31 10.1186/s13068-014-0133-7 COLLEGE NANME Medicine COLLEGE CODE PMSC Swansea University 2021-10-26T15:37:28.0047530 2014-10-06T12:41:13.7419160 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Claire Hull 1 Joel Loveridge 0000-0002-8528-4019 2 Nicola J Rolley 3 Iain S Donnison 4 Steven Kelly 0000-0001-7991-5040 5 Diane Kelly 6
title Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
spellingShingle Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
Claire Hull
Joel Loveridge
Steven Kelly
Diane Kelly
title_short Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
title_full Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
title_fullStr Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
title_full_unstemmed Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
title_sort Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
author_id_str_mv 6c495cb489b67bc9bb3f746975c4ff19
5dd2760b388ec3cc2af33bb62f3f151a
b17cebaf09b4d737b9378a3581e3de93
5ccf81e5d5beedf32ef8d7c3d7ac6c8c
author_id_fullname_str_mv 6c495cb489b67bc9bb3f746975c4ff19_***_Claire Hull
5dd2760b388ec3cc2af33bb62f3f151a_***_Joel Loveridge
b17cebaf09b4d737b9378a3581e3de93_***_Steven Kelly
5ccf81e5d5beedf32ef8d7c3d7ac6c8c_***_Diane Kelly
author Claire Hull
Joel Loveridge
Steven Kelly
Diane Kelly
author2 Claire Hull
Joel Loveridge
Nicola J Rolley
Iain S Donnison
Steven Kelly
Diane Kelly
format Journal article
container_title Biotechnology for Biofuels
container_volume 7
container_issue 1
container_start_page 133
publishDate 2014
institution Swansea University
doi_str_mv 10.1186/s13068-014-0133-7
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine habitats, sustainable sources of squalene are required. This study investigated a microbial biorefinery approach to co-production of squalene and ethanol using an engineered strain of the yeast Saccharomyces cerevisiae.
published_date 2014-10-31T03:21:50Z
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score 11.012678

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