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A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic

D. Williams, S. Flory, R. King, M. Thornton, J. Dingley, John Dingley

Anaesthesia, Volume: 65, Issue: 3, Pages: 235 - 242

Swansea University Author: John Dingley

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DOI (Published version): 10.1111/j.1365-2044.2009.06207.x

Abstract

The UK influenza pandemic plan predicts up to 750,000 additional deaths with hospitals prioritising patients against inadequate resources. We investigated three prototype low-cost, gas-efficient, pneumatic ventilators in a test lung model at different compliance and rate settings. Mean (SD) oxygen c...

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Published in: Anaesthesia
ISSN: 00032409 13652044
Published: 2010
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URI: https://cronfa.swan.ac.uk/Record/cronfa27470
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first_indexed 2016-04-27T01:14:57Z
last_indexed 2018-06-30T04:06:33Z
id cronfa27470
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spelling 2018-06-29T19:58:21.3248314 v2 27470 2016-04-26 A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic 1283ffdd09b091ec57ec3e235a48cfcc John Dingley John Dingley true false 2016-04-26 PMSC The UK influenza pandemic plan predicts up to 750,000 additional deaths with hospitals prioritising patients against inadequate resources. We investigated three prototype low-cost, gas-efficient, pneumatic ventilators in a test lung model at different compliance and rate settings. Mean (SD) oxygen consumption was 0.913 (0.198) and 1.119 (0.267) l.min(-1) at tidal volumes of 500 ml and 700 ml respectively. Values of F(I)o(2) increased marginally as lung compliance reduced, reflecting the increased ventilator workload and consequent increased enrichment of breathing gas by waste oxygen from the pneumatic mechanism. We also demonstrated that a stable nitric oxide concentration could be delivered by this design following volumetric principles. It is possible to make a gas-efficient ventilator costing less than 200 pounds from industrial components for use where oxygen is available at 2-4 bar, with no pressurised air or electrical requirements. Such a device could be mass-produced for crises characterised by an overwhelming demand for mechanical ventilation and a limited oxygen supply. Journal Article Anaesthesia 65 3 235 242 00032409 13652044 31 12 2010 2010-12-31 10.1111/j.1365-2044.2009.06207.x COLLEGE NANME Medicine COLLEGE CODE PMSC Swansea University 2018-06-29T19:58:21.3248314 2016-04-26T22:43:02.5021615 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine D. Williams 1 S. Flory 2 R. King 3 M. Thornton 4 J. Dingley 5 John Dingley 6
title A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
spellingShingle A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
John Dingley
title_short A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
title_full A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
title_fullStr A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
title_full_unstemmed A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
title_sort A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic
author_id_str_mv 1283ffdd09b091ec57ec3e235a48cfcc
author_id_fullname_str_mv 1283ffdd09b091ec57ec3e235a48cfcc_***_John Dingley
author John Dingley
author2 D. Williams
S. Flory
R. King
M. Thornton
J. Dingley
John Dingley
format Journal article
container_title Anaesthesia
container_volume 65
container_issue 3
container_start_page 235
publishDate 2010
institution Swansea University
issn 00032409
13652044
doi_str_mv 10.1111/j.1365-2044.2009.06207.x
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description The UK influenza pandemic plan predicts up to 750,000 additional deaths with hospitals prioritising patients against inadequate resources. We investigated three prototype low-cost, gas-efficient, pneumatic ventilators in a test lung model at different compliance and rate settings. Mean (SD) oxygen consumption was 0.913 (0.198) and 1.119 (0.267) l.min(-1) at tidal volumes of 500 ml and 700 ml respectively. Values of F(I)o(2) increased marginally as lung compliance reduced, reflecting the increased ventilator workload and consequent increased enrichment of breathing gas by waste oxygen from the pneumatic mechanism. We also demonstrated that a stable nitric oxide concentration could be delivered by this design following volumetric principles. It is possible to make a gas-efficient ventilator costing less than 200 pounds from industrial components for use where oxygen is available at 2-4 bar, with no pressurised air or electrical requirements. Such a device could be mass-produced for crises characterised by an overwhelming demand for mechanical ventilation and a limited oxygen supply.
published_date 2010-12-31T03:33:18Z
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score 11.012678

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