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In-situ synthesis of magnetic iron-oxide nanoparticle-nanofibre composites using electrospinning

Luke Burke, Chris J. Mortimer, Daniel Curtis Orcid Logo, Aled R. Lewis, Rhodri Williams Orcid Logo, Karl Hawkins Orcid Logo, Thierry Maffeis Orcid Logo, Chris J. Wright, Christopher Wright Orcid Logo

Materials Science and Engineering: C, Volume: 70, Pages: 512 - 519

Swansea University Authors: Daniel Curtis Orcid Logo, Rhodri Williams Orcid Logo, Karl Hawkins Orcid Logo, Thierry Maffeis Orcid Logo, Christopher Wright Orcid Logo

Abstract

We demonstrate a facile, one-step process to form polymer scaffolds composed of magnetic iron oxide nanoparticles (MNPs) contained within electrospun nano- and micro-fibres of two biocompatible polymers, Poly(ethylene oxide) (PEO) and Poly(vinyl pyrrolidone) (PVP). This was achieved with both needle...

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Published in: Materials Science and Engineering: C
ISSN: 0928-4931
Published: 2017
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa29839
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Abstract: We demonstrate a facile, one-step process to form polymer scaffolds composed of magnetic iron oxide nanoparticles (MNPs) contained within electrospun nano- and micro-fibres of two biocompatible polymers, Poly(ethylene oxide) (PEO) and Poly(vinyl pyrrolidone) (PVP). This was achieved with both needle and free-surface electrospinning systems demonstrating the scalability of the composite fibre manufacture; a 228 fold increase in fibre fabrication was observed for the free-surface system. In all cases the nanoparticle-nanofibre composite scaffolds displayed morphological properties as good as or better than those previously described and fabricated using complex multi-stage techniques. Fibres produced had an average diameter (Needle-spun: 125 ± 18 nm (PEO) and 1.58 ± 0.28 μm (PVP); Free-surface electrospun: 155 ± 31 nm (PEO)) similar to that reported previously, were smooth with no bead defects. Nanoparticle-nanofibre composites were characterised using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), dynamic light scattering (DLS) (Nanoparticle average diameter ranging from 8 ± 3 nm to 27 ± 5 nm), XRD (Phase of iron oxide nanoparticles identified as magnetite) and nuclear magnetic resonance relaxation measurements (NMR) (T1/T2: 32.44 for PEO fibres containing MNPs) were used to verify the magnetic behaviour of MNPs. This study represents a significant step forward for production rates of magnetic nanoparticle-nanofibre composite scaffolds by the electrospinning technique.
College: College of Engineering
Start Page: 512
End Page: 519