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Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review

M. L. Eckstein Orcid Logo, D. M. Williams, L. K. O'Neil, J. Hayes, Jeffrey Stephens Orcid Logo, Richard Bracken Orcid Logo

Diabetic Medicine, Volume: 36, Issue: 3, Pages: 349 - 358

Swansea University Authors: Jeffrey Stephens Orcid Logo, Richard Bracken Orcid Logo

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DOI (Published version): 10.1111/dme.13865

Abstract

In the UK the National Institute of Health and Care Excellence (NICE) advocates intensive lifestyle programmes that attain the levels of daily physical activity set out by the Chief Medical Officer as a first‐line strategy for improving the health of people at risk of developing diabetes or reducing...

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Published in: Diabetic Medicine
ISSN: 0742-3071 1464-5491
Published: Wiley 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa47934
first_indexed 2018-12-11T20:05:07Z
last_indexed 2024-11-14T11:56:20Z
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spelling 2024-01-08T10:27:08.3941524 v2 47934 2018-12-11 Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review 5219d126f97f8f884bdb622099bd41de 0000-0003-2228-086X Jeffrey Stephens Jeffrey Stephens true false f5da81cd18adfdedb2ccb845bddc12f7 0000-0002-6986-6449 Richard Bracken Richard Bracken true false 2018-12-11 MEDS In the UK the National Institute of Health and Care Excellence (NICE) advocates intensive lifestyle programmes that attain the levels of daily physical activity set out by the Chief Medical Officer as a first‐line strategy for improving the health of people at risk of developing diabetes or reducing the risk of development of Type 2 diabetes. For people with Type 2 diabetes, lifestyle measures complement pharmacological treatments that include both oral and injectable therapies. In line with this, NICE guidelines also support intensification of efforts to improve patient lifestyle along with these glucose‐lowering therapies. There is a paucity of evidence, however, in the available published literature examining the association between glucose‐lowering therapies and exercise metabolism. In the present review we explore the current knowledge with regard to the potential interactions of oral and non‐insulin injectable therapies with physical activity in people at risk of, or who have, Type 2 diabetes, and present evidence that may inform healthcare professionals of the need to monitor patients more closely in their adaptation to both pharmacological therapy and physical activity. Journal Article Diabetic Medicine 36 3 349 358 Wiley 0742-3071 1464-5491 1 3 2019 2019-03-01 10.1111/dme.13865 http://dx.doi.org/10.1111/dme.13865 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2024-01-08T10:27:08.3941524 2018-12-11T14:39:41.3342950 Faculty of Science and Engineering M. L. Eckstein 0000-0003-0320-8408 1 D. M. Williams 2 L. K. O'Neil 3 J. Hayes 4 Jeffrey Stephens 0000-0003-2228-086X 5 Richard Bracken 0000-0002-6986-6449 6 0047934-11122018144359.pdf eckstein2018.pdf 2018-12-11T14:43:59.1630000 Output 567959 application/pdf Accepted Manuscript true 2019-12-07T00:00:00.0000000 true eng
title Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
spellingShingle Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
Jeffrey Stephens
Richard Bracken
title_short Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_full Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_fullStr Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_full_unstemmed Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_sort Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
author_id_str_mv 5219d126f97f8f884bdb622099bd41de
f5da81cd18adfdedb2ccb845bddc12f7
author_id_fullname_str_mv 5219d126f97f8f884bdb622099bd41de_***_Jeffrey Stephens
f5da81cd18adfdedb2ccb845bddc12f7_***_Richard Bracken
author Jeffrey Stephens
Richard Bracken
author2 M. L. Eckstein
D. M. Williams
L. K. O'Neil
J. Hayes
Jeffrey Stephens
Richard Bracken
format Journal article
container_title Diabetic Medicine
container_volume 36
container_issue 3
container_start_page 349
publishDate 2019
institution Swansea University
issn 0742-3071
1464-5491
doi_str_mv 10.1111/dme.13865
publisher Wiley
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
url http://dx.doi.org/10.1111/dme.13865
document_store_str 1
active_str 0
description In the UK the National Institute of Health and Care Excellence (NICE) advocates intensive lifestyle programmes that attain the levels of daily physical activity set out by the Chief Medical Officer as a first‐line strategy for improving the health of people at risk of developing diabetes or reducing the risk of development of Type 2 diabetes. For people with Type 2 diabetes, lifestyle measures complement pharmacological treatments that include both oral and injectable therapies. In line with this, NICE guidelines also support intensification of efforts to improve patient lifestyle along with these glucose‐lowering therapies. There is a paucity of evidence, however, in the available published literature examining the association between glucose‐lowering therapies and exercise metabolism. In the present review we explore the current knowledge with regard to the potential interactions of oral and non‐insulin injectable therapies with physical activity in people at risk of, or who have, Type 2 diabetes, and present evidence that may inform healthcare professionals of the need to monitor patients more closely in their adaptation to both pharmacological therapy and physical activity.
published_date 2019-03-01T19:44:39Z
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score 11.048042

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