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Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review / Richard, Bracken; Jeffrey, Stephens

Diabetic Medicine

Swansea University Authors: Richard, Bracken, Jeffrey, Stephens

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DOI (Published version): 10.1111/dme.13865

Abstract

In the UK the National Institute of Health and Care Excellence (NICE) advocates intensive lifestyle programmes that attain the levels of daily physical activity set out by the Chief Medical Officer as a first‐line strategy for improving the health of people at risk of developing diabetes or reducing...

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Published in: Diabetic Medicine
ISSN: 0742-3071 1464-5491
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URI: https://cronfa.swan.ac.uk/Record/cronfa47934
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first_indexed 2018-12-11T20:05:07Z
last_indexed 2019-01-28T14:02:26Z
id cronfa47934
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spelling 2019-01-28T12:15:28.5662675 v2 47934 2018-12-11 Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review f5da81cd18adfdedb2ccb845bddc12f7 0000-0002-6986-6449 Richard Bracken Richard Bracken true false 5219d126f97f8f884bdb622099bd41de 0000-0003-2228-086X Jeffrey Stephens Jeffrey Stephens true false 2018-12-11 STSC In the UK the National Institute of Health and Care Excellence (NICE) advocates intensive lifestyle programmes that attain the levels of daily physical activity set out by the Chief Medical Officer as a first‐line strategy for improving the health of people at risk of developing diabetes or reducing the risk of development of Type 2 diabetes. For people with Type 2 diabetes, lifestyle measures complement pharmacological treatments that include both oral and injectable therapies. In line with this, NICE guidelines also support intensification of efforts to improve patient lifestyle along with these glucose‐lowering therapies. There is a paucity of evidence, however, in the available published literature examining the association between glucose‐lowering therapies and exercise metabolism. In the present review we explore the current knowledge with regard to the potential interactions of oral and non‐insulin injectable therapies with physical activity in people at risk of, or who have, Type 2 diabetes, and present evidence that may inform healthcare professionals of the need to monitor patients more closely in their adaptation to both pharmacological therapy and physical activity. Journal Article Diabetic Medicine 0742-3071 1464-5491 0 0 0 0001-01-01 10.1111/dme.13865 COLLEGE NANME Sports Science COLLEGE CODE STSC Swansea University 2019-01-28T12:15:28.5662675 2018-12-11T14:39:41.3342950 College of Engineering Sports Science M. L. Eckstein 1 D. M. Williams 2 L. K. O'Neil 3 J. Hayes 4 J. W. Stephens 5 R. M. Bracken 6 Richard Bracken 0000-0002-6986-6449 7 Jeffrey Stephens 0000-0003-2228-086X 8 0047934-11122018144359.pdf eckstein2018.pdf 2018-12-11T14:43:59.1630000 Output 567959 application/pdf Accepted Manuscript true 2019-12-07T00:00:00.0000000 true eng
title Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
spellingShingle Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
Richard, Bracken
Jeffrey, Stephens
title_short Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_full Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_fullStr Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_full_unstemmed Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
title_sort Physical exercise and non‐insulin glucose‐lowering therapies in the management of Type 2 diabetes mellitus: a clinical review
author_id_str_mv f5da81cd18adfdedb2ccb845bddc12f7
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author_id_fullname_str_mv f5da81cd18adfdedb2ccb845bddc12f7_***_Richard, Bracken
5219d126f97f8f884bdb622099bd41de_***_Jeffrey, Stephens
author Richard, Bracken
Jeffrey, Stephens
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description In the UK the National Institute of Health and Care Excellence (NICE) advocates intensive lifestyle programmes that attain the levels of daily physical activity set out by the Chief Medical Officer as a first‐line strategy for improving the health of people at risk of developing diabetes or reducing the risk of development of Type 2 diabetes. For people with Type 2 diabetes, lifestyle measures complement pharmacological treatments that include both oral and injectable therapies. In line with this, NICE guidelines also support intensification of efforts to improve patient lifestyle along with these glucose‐lowering therapies. There is a paucity of evidence, however, in the available published literature examining the association between glucose‐lowering therapies and exercise metabolism. In the present review we explore the current knowledge with regard to the potential interactions of oral and non‐insulin injectable therapies with physical activity in people at risk of, or who have, Type 2 diabetes, and present evidence that may inform healthcare professionals of the need to monitor patients more closely in their adaptation to both pharmacological therapy and physical activity.
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