Journal article 907 views 132 downloads
Pre-Exercise Blood Glucose Levels Determine the Amount of Orally Administered Carbohydrates during Physical Exercise in Individuals with Type 1 Diabetes—A Randomized Cross-Over Trial
Othmar Moser,
Max L. Eckstein,
Alexander Mueller,
Philipp Birnbaumer,
Felix Aberer,
Gerd Koehler,
Caren Sourij,
Harald Kojzar,
Peter Pferschy,
Pavel Dietz,
Richard Bracken
,
Peter Hofmann,
Harald Sourij
Nutrients, Volume: 11, Issue: 6
Swansea University Author:
Richard Bracken
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DOI (Published version): 10.3390/nu11061287
Abstract
The aim of the study was to assess the amount of orally administered carbohydrates needed to maintain euglycemia during moderate-intensity exercise in individuals with type 1 diabetes. Nine participants with type 1 diabetes (four women, age 32.1 ± 9.0 years, BMI 25.5 ± 3.9 kg/m2, HbA1c 55 ± 7 mmol/m...
Published in: | Nutrients |
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ISSN: | 2072-6643 |
Published: |
2019
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Online Access: |
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URI: | https://cronfa.swan.ac.uk/Record/cronfa50972 |
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Abstract: |
The aim of the study was to assess the amount of orally administered carbohydrates needed to maintain euglycemia during moderate-intensity exercise in individuals with type 1 diabetes. Nine participants with type 1 diabetes (four women, age 32.1 ± 9.0 years, BMI 25.5 ± 3.9 kg/m2, HbA1c 55 ± 7 mmol/mol (7.2 ± 0.6%)) on insulin Degludec were randomized to cycle for 55 min at moderate intensity (63 ± 7% VO2peak) for five consecutive days on either 75% or 100% of their regular basal insulin dose. The impact of pre-exercise blood glucose concentration on the carbohydrate requirement was analyzed by one-way ANOVA stratified for pre-exercise blood glucose quartiles. The effect of the basal insulin dose on the amount of orally administered carbohydrates was evaluated by Wilcoxon matched-pairs signed-rank test. The amount of orally administered carbohydrates during the continuous exercise sessions was similar for both trial arms (75% or 100% basal insulin) with median [IQR] of 36 g (9–62 g) and 36 g (9–66 g) (p = 0.78). The amount of orally administered carbohydrates was determined by pre-exercise blood glucose concentration for both trial arms (p = 0.03). Our study elucidated the importance of pre-exercise glucose concentration related orally administered carbohydrates to maintain euglycemia during exercise in individuals with type 1 diabetes. |
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Keywords: |
carbohydrates; exercise; type 1 diabetes; euglycemia; insulin |
Issue: |
6 |