No Cover Image

Journal article 395 views 101 downloads

Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices

Angela F. De Fazio, Afaf H. El-Sagheer, Jason S. Kahn, Iris Nandhakumar, Matthew Burton Orcid Logo, Tom Brown, Otto L. Muskens, Oleg Gang, Antonios G. Kanaras

ACS Nano

Swansea University Author: Matthew Burton Orcid Logo

  • Light-inducedreversibleDNAligationofgoldnanoparticlesuperlattices.docx

    Microsoft Word | Accepted Manuscript

    This document is the unedited Author’s version of a Submitted Work that was subsequently accepted for publication in ACS Nano, copyright © American Chemical Society after peer review. To access the final edited and published work see https://pubs.acs.org/doi/abs/10.1021/acsnano.9b01294.

    Download (2.6MB)
  • defazio2-19(2).pdf

    PDF | Version of Record

    Distributed under the terms of a Creative Commons Attribution (CC-BY-4.0)

    Download (6.72MB)

Check full text

DOI (Published version): 10.1021/acsnano.9b01294

Abstract

DNA-mediated self-assembly of nanoparticles has been of great interest because it enables access to nanoparticle superstructures that cannot be synthesized otherwise. However, the programmability of higher order nanoparticle structures can be easily lost under DNA denaturing conditions. Here, we dem...

Full description

Published in: ACS Nano
ISSN: 1936-0851 1936-086X
Published: American Chemical Society 2019
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa50091
Tags: Add Tag
No Tags, Be the first to tag this record!
first_indexed 2019-04-26T13:38:01Z
last_indexed 2019-07-17T15:34:21Z
id cronfa50091
recordtype SURis
fullrecord <?xml version="1.0"?><rfc1807><datestamp>2019-07-17T11:48:48.0081126</datestamp><bib-version>v2</bib-version><id>50091</id><entry>2019-04-25</entry><title>Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices</title><swanseaauthors><author><sid>2deade2806e39b1f749e9cf67ac640b2</sid><ORCID>0000-0002-0376-6322</ORCID><firstname>Matthew</firstname><surname>Burton</surname><name>Matthew Burton</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2019-04-25</date><deptcode>MTLS</deptcode><abstract>DNA-mediated self-assembly of nanoparticles has been of great interest because it enables access to nanoparticle superstructures that cannot be synthesized otherwise. However, the programmability of higher order nanoparticle structures can be easily lost under DNA denaturing conditions. Here, we demonstrate that light can be employed as an external stimulus to master the stability of nanoparticle superlattices (SLs) via the promotion of a reversible photoligation of DNA in SLs. The oligonucleotides attached to the nanoparticles are encoded to ligate using 365 nm light, effectively locking the SLs and rendering them stable under DNA denaturing conditions. The reversible process of unlocking these structures is possible by irradiation with light at 315 nm, recovering the structures to their natural state. Our work inspires an alternative research direction toward postassembly manipulation of nanoparticle superstructures using external stimuli as a tool to enrich the library of additional material forms and their application in different media and environments.</abstract><type>Journal Article</type><journal>ACS Nano</journal><publisher>American Chemical Society</publisher><issnPrint>1936-0851</issnPrint><issnElectronic>1936-086X</issnElectronic><keywords>DNA, nanoparticles, photochemical ligation, self-assembly, superlattices</keywords><publishedDay>8</publishedDay><publishedMonth>4</publishedMonth><publishedYear>2019</publishedYear><publishedDate>2019-04-08</publishedDate><doi>10.1021/acsnano.9b01294</doi><url>https://pubs.acs.org/doi/abs/10.1021/acsnano.9b01294</url><notes/><college>COLLEGE NANME</college><department>Materials Science and Engineering</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>MTLS</DepartmentCode><institution>Swansea University</institution><apcterm/><lastEdited>2019-07-17T11:48:48.0081126</lastEdited><Created>2019-04-25T10:35:21.6526833</Created><path><level id="1">Faculty of Science and Engineering</level><level id="2">School of Engineering and Applied Sciences - Materials Science and Engineering</level></path><authors><author><firstname>Angela F.</firstname><surname>De Fazio</surname><order>1</order></author><author><firstname>Afaf H.</firstname><surname>El-Sagheer</surname><order>2</order></author><author><firstname>Jason S.</firstname><surname>Kahn</surname><order>3</order></author><author><firstname>Iris</firstname><surname>Nandhakumar</surname><order>4</order></author><author><firstname>Matthew</firstname><surname>Burton</surname><orcid>0000-0002-0376-6322</orcid><order>5</order></author><author><firstname>Tom</firstname><surname>Brown</surname><order>6</order></author><author><firstname>Otto L.</firstname><surname>Muskens</surname><order>7</order></author><author><firstname>Oleg</firstname><surname>Gang</surname><order>8</order></author><author><firstname>Antonios G.</firstname><surname>Kanaras</surname><order>9</order></author></authors><documents><document><filename>0050091-25042019151752.docx</filename><originalFilename>Light-inducedreversibleDNAligationofgoldnanoparticlesuperlattices.docx</originalFilename><uploaded>2019-04-25T15:17:52.6330000</uploaded><type>Output</type><contentLength>2697036</contentLength><contentType>application/vnd.openxmlformats-officedocument.wordprocessingml.document</contentType><version>Accepted Manuscript</version><cronfaStatus>true</cronfaStatus><embargoDate>2020-04-01T00:00:00.0000000</embargoDate><documentNotes>This document is the unedited Author&#x2019;s version of a Submitted Work that was subsequently accepted for publication in ACS Nano, copyright &#xA9; American Chemical Society after peer review. To access the final edited and published work see https://pubs.acs.org/doi/abs/10.1021/acsnano.9b01294.</documentNotes><copyrightCorrect>true</copyrightCorrect><language>eng</language></document><document><filename>0050091-13052019132226.pdf</filename><originalFilename>defazio2-19(2).pdf</originalFilename><uploaded>2019-05-13T13:22:26.8170000</uploaded><type>Output</type><contentLength>7219931</contentLength><contentType>application/pdf</contentType><version>Version of Record</version><cronfaStatus>true</cronfaStatus><embargoDate>2019-05-13T00:00:00.0000000</embargoDate><documentNotes>Distributed under the terms of a Creative Commons Attribution (CC-BY-4.0)</documentNotes><copyrightCorrect>true</copyrightCorrect><language>eng</language></document></documents><OutputDurs/></rfc1807>
spelling 2019-07-17T11:48:48.0081126 v2 50091 2019-04-25 Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices 2deade2806e39b1f749e9cf67ac640b2 0000-0002-0376-6322 Matthew Burton Matthew Burton true false 2019-04-25 MTLS DNA-mediated self-assembly of nanoparticles has been of great interest because it enables access to nanoparticle superstructures that cannot be synthesized otherwise. However, the programmability of higher order nanoparticle structures can be easily lost under DNA denaturing conditions. Here, we demonstrate that light can be employed as an external stimulus to master the stability of nanoparticle superlattices (SLs) via the promotion of a reversible photoligation of DNA in SLs. The oligonucleotides attached to the nanoparticles are encoded to ligate using 365 nm light, effectively locking the SLs and rendering them stable under DNA denaturing conditions. The reversible process of unlocking these structures is possible by irradiation with light at 315 nm, recovering the structures to their natural state. Our work inspires an alternative research direction toward postassembly manipulation of nanoparticle superstructures using external stimuli as a tool to enrich the library of additional material forms and their application in different media and environments. Journal Article ACS Nano American Chemical Society 1936-0851 1936-086X DNA, nanoparticles, photochemical ligation, self-assembly, superlattices 8 4 2019 2019-04-08 10.1021/acsnano.9b01294 https://pubs.acs.org/doi/abs/10.1021/acsnano.9b01294 COLLEGE NANME Materials Science and Engineering COLLEGE CODE MTLS Swansea University 2019-07-17T11:48:48.0081126 2019-04-25T10:35:21.6526833 Faculty of Science and Engineering School of Engineering and Applied Sciences - Materials Science and Engineering Angela F. De Fazio 1 Afaf H. El-Sagheer 2 Jason S. Kahn 3 Iris Nandhakumar 4 Matthew Burton 0000-0002-0376-6322 5 Tom Brown 6 Otto L. Muskens 7 Oleg Gang 8 Antonios G. Kanaras 9 0050091-25042019151752.docx Light-inducedreversibleDNAligationofgoldnanoparticlesuperlattices.docx 2019-04-25T15:17:52.6330000 Output 2697036 application/vnd.openxmlformats-officedocument.wordprocessingml.document Accepted Manuscript true 2020-04-01T00:00:00.0000000 This document is the unedited Author’s version of a Submitted Work that was subsequently accepted for publication in ACS Nano, copyright © American Chemical Society after peer review. To access the final edited and published work see https://pubs.acs.org/doi/abs/10.1021/acsnano.9b01294. true eng 0050091-13052019132226.pdf defazio2-19(2).pdf 2019-05-13T13:22:26.8170000 Output 7219931 application/pdf Version of Record true 2019-05-13T00:00:00.0000000 Distributed under the terms of a Creative Commons Attribution (CC-BY-4.0) true eng
title Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
spellingShingle Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
Matthew Burton
title_short Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
title_full Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
title_fullStr Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
title_full_unstemmed Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
title_sort Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices
author_id_str_mv 2deade2806e39b1f749e9cf67ac640b2
author_id_fullname_str_mv 2deade2806e39b1f749e9cf67ac640b2_***_Matthew Burton
author Matthew Burton
author2 Angela F. De Fazio
Afaf H. El-Sagheer
Jason S. Kahn
Iris Nandhakumar
Matthew Burton
Tom Brown
Otto L. Muskens
Oleg Gang
Antonios G. Kanaras
format Journal article
container_title ACS Nano
publishDate 2019
institution Swansea University
issn 1936-0851
1936-086X
doi_str_mv 10.1021/acsnano.9b01294
publisher American Chemical Society
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Materials Science and Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Materials Science and Engineering
url https://pubs.acs.org/doi/abs/10.1021/acsnano.9b01294
document_store_str 1
active_str 0
description DNA-mediated self-assembly of nanoparticles has been of great interest because it enables access to nanoparticle superstructures that cannot be synthesized otherwise. However, the programmability of higher order nanoparticle structures can be easily lost under DNA denaturing conditions. Here, we demonstrate that light can be employed as an external stimulus to master the stability of nanoparticle superlattices (SLs) via the promotion of a reversible photoligation of DNA in SLs. The oligonucleotides attached to the nanoparticles are encoded to ligate using 365 nm light, effectively locking the SLs and rendering them stable under DNA denaturing conditions. The reversible process of unlocking these structures is possible by irradiation with light at 315 nm, recovering the structures to their natural state. Our work inspires an alternative research direction toward postassembly manipulation of nanoparticle superstructures using external stimuli as a tool to enrich the library of additional material forms and their application in different media and environments.
published_date 2019-04-08T04:01:24Z
_version_ 1763753155222306816
score 10.998116

Similar Items