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Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations / Giovanni Pomponio; Silvia Tedesco; Angela Peghetti; Tommaso Bianchi; Sara Rowan; Alessandro Greco; Keith Cutting; Patricia Price; Zena Moore; Armando Gabrielli; Randall Wolcott; Tricia Price

Journal of Wound Care, Volume: 28, Issue: Sup1, Pages: S26 - S31

Swansea University Author: Tricia, Price

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Abstract

Objective:: To produce recommendations for the design of reliable and informative clinical investigations in chronic wound infection. Method: A multidisciplinary panel of international experts from four countries (Italy, UK, Ireland and the US) were involved in a detailed, semi-structured discussion...

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Published in: Journal of Wound Care
ISSN: 0969-0700 2052-2916
Published: 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa50575
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Abstract: Objective:: To produce recommendations for the design of reliable and informative clinical investigations in chronic wound infection. Method: A multidisciplinary panel of international experts from four countries (Italy, UK, Ireland and the US) were involved in a detailed, semi-structured discussion on how to better select and describe a target population, interventions and outcomes, and which infection-related criteria to apply in order to achieve a high-quality trial. Consent among the experts was measured using the Delphi method and GRADE Working Group suggestions. The project was fully supported by AISLeC 2016 (Italian Nursing Society for Wound Care Study). Results: In total, 37 recommendations achieved substantial agreement among the experts; 10 concerned the most appropriate description and selection of a target population, four related to interventions and 15 to outcomes. A further eight statements about critical methodological points were approved. Conclusion: Developing recommendations in a systematic manner through a representative group of experts could generate tools for improving the design of clinical trials in this challenging area.
College: College of Human and Health Sciences
Issue: Sup1
Start Page: S26
End Page: S31