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Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations

Giovanni Pomponio, Silvia Tedesco, Angela Peghetti, Tommaso Bianchi, Sara Rowan, Alessandro Greco, Keith Cutting, Patricia Price, Zena Moore, Armando Gabrielli, Randall Wolcott, Tricia Price

Journal of Wound Care, Volume: 28, Issue: Sup1, Pages: S26 - S31

Swansea University Author: Tricia Price

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DOI (Published version): 10.12968/jowc.2019.28.Sup1.S26

Abstract

Objective:: To produce recommendations for the design of reliable and informative clinical investigations in chronic wound infection. Method: A multidisciplinary panel of international experts from four countries (Italy, UK, Ireland and the US) were involved in a detailed, semi-structured discussion...

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Published in: Journal of Wound Care
ISSN: 0969-0700 2052-2916
Published: 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa50575
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first_indexed 2019-06-05T11:07:51Z
last_indexed 2020-09-29T03:10:42Z
id cronfa50575
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spelling v2 50575 2019-05-30 Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations 72b4943af96c97ef72977c31b9c29624 Tricia Price Tricia Price true false 2019-05-30 FGMHL Objective:: To produce recommendations for the design of reliable and informative clinical investigations in chronic wound infection. Method: A multidisciplinary panel of international experts from four countries (Italy, UK, Ireland and the US) were involved in a detailed, semi-structured discussion on how to better select and describe a target population, interventions and outcomes, and which infection-related criteria to apply in order to achieve a high-quality trial. Consent among the experts was measured using the Delphi method and GRADE Working Group suggestions. The project was fully supported by AISLeC 2016 (Italian Nursing Society for Wound Care Study). Results: In total, 37 recommendations achieved substantial agreement among the experts; 10 concerned the most appropriate description and selection of a target population, four related to interventions and 15 to outcomes. A further eight statements about critical methodological points were approved. Conclusion: Developing recommendations in a systematic manner through a representative group of experts could generate tools for improving the design of clinical trials in this challenging area. Journal Article Journal of Wound Care 28 Sup1 S26 S31 0969-0700 2052-2916 31 12 2019 2019-12-31 10.12968/jowc.2019.28.Sup1.S26 COLLEGE NANME Medicine, Health and Life Science - Faculty COLLEGE CODE FGMHL Swansea University 2023-06-28T15:27:12.4532318 2019-05-30T15:09:22.3899271 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Giovanni Pomponio 1 Silvia Tedesco 2 Angela Peghetti 3 Tommaso Bianchi 4 Sara Rowan 5 Alessandro Greco 6 Keith Cutting 7 Patricia Price 8 Zena Moore 9 Armando Gabrielli 10 Randall Wolcott 11 Tricia Price 12
title Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
spellingShingle Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
Tricia Price
title_short Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
title_full Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
title_fullStr Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
title_full_unstemmed Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
title_sort Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations
author_id_str_mv 72b4943af96c97ef72977c31b9c29624
author_id_fullname_str_mv 72b4943af96c97ef72977c31b9c29624_***_Tricia Price
author Tricia Price
author2 Giovanni Pomponio
Silvia Tedesco
Angela Peghetti
Tommaso Bianchi
Sara Rowan
Alessandro Greco
Keith Cutting
Patricia Price
Zena Moore
Armando Gabrielli
Randall Wolcott
Tricia Price
format Journal article
container_title Journal of Wound Care
container_volume 28
container_issue Sup1
container_start_page S26
publishDate 2019
institution Swansea University
issn 0969-0700
2052-2916
doi_str_mv 10.12968/jowc.2019.28.Sup1.S26
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description Objective:: To produce recommendations for the design of reliable and informative clinical investigations in chronic wound infection. Method: A multidisciplinary panel of international experts from four countries (Italy, UK, Ireland and the US) were involved in a detailed, semi-structured discussion on how to better select and describe a target population, interventions and outcomes, and which infection-related criteria to apply in order to achieve a high-quality trial. Consent among the experts was measured using the Delphi method and GRADE Working Group suggestions. The project was fully supported by AISLeC 2016 (Italian Nursing Society for Wound Care Study). Results: In total, 37 recommendations achieved substantial agreement among the experts; 10 concerned the most appropriate description and selection of a target population, four related to interventions and 15 to outcomes. A further eight statements about critical methodological points were approved. Conclusion: Developing recommendations in a systematic manner through a representative group of experts could generate tools for improving the design of clinical trials in this challenging area.
published_date 2019-12-31T15:27:08Z
_version_ 1769956891588296704
score 11.036334

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