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How biomechanical properties of red blood cells change with temperature

Adesola Ademiloye Orcid Logo

Proceedings of the 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2019), Volume: 2, Pages: 686 - 689

Swansea University Author: Adesola Ademiloye Orcid Logo

Abstract

In recent decades, the biomechanical properties of human red blood cells (RBCs) have been greatly explored by numerous researchers for diverse reasons. In normal physiological conditions, RBCs undergoes large deformation when traversing thin microcapillaries, however, upon infection by different blo...

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Published in: Proceedings of the 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2019)
ISBN: 978-0-9562914-5-5
ISSN: 2227-3085 2227-9385
Published: United Kingdom Zeta Computational Resources Ltd., Cardiff, UK 2019
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa52593
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Abstract: In recent decades, the biomechanical properties of human red blood cells (RBCs) have been greatly explored by numerous researchers for diverse reasons. In normal physiological conditions, RBCs undergoes large deformation when traversing thin microcapillaries, however, upon infection by different blood-related diseases such as malaria, they experience impaired deformability. This paper examines how biomechanical properties of RBCs change with temperature using a multiscale meshfree method. The multiscale meshfree method offers improved accuracy and better computational efficiency as it incorporates RBC membrane microstructural configuration into its constitutive formulation, thereby providing better insights into the changes on the atomistic level.
College: Faculty of Science and Engineering
Start Page: 686
End Page: 689