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Conference Paper/Proceeding/Abstract 671 views

The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD

Matthew Hitchings Orcid Logo, Andrew Cunningham, Sue Chandler, Dean Harris Orcid Logo

Falk Foundation Symposium 217: West Meets East: Functional Meets Organic in Gastrointestinal Diseases

Swansea University Authors: Matthew Hitchings Orcid Logo, Dean Harris Orcid Logo

Abstract

Faecal Microbiota Transplantation (FMT) was first recorded over 2000 years ago for the treatment of severe diarrhoea. FMT is an infusion of a faecal suspension from a healthy individual to the GI tract of a recipient patient, in order to treat a disorder associated with an alteration of gut microbio...

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Published in: Falk Foundation Symposium 217: West Meets East: Functional Meets Organic in Gastrointestinal Diseases
Published: 2019
Online Access: http://www.falk-foundation-symposia.org/symposia-and-workshops/2019/?L=1
URI: https://cronfa.swan.ac.uk/Record/cronfa53364
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first_indexed 2020-01-27T13:30:32Z
last_indexed 2020-07-08T19:15:55Z
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spelling 2020-07-08T15:05:40.6537039 v2 53364 2020-01-27 The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD be98847c72c14a731c4a6b7bc02b3bcf 0000-0002-5527-4709 Matthew Hitchings Matthew Hitchings true false 731533890c5123febe4f65dffd369f7b 0000-0003-2673-8946 Dean Harris Dean Harris true false 2020-01-27 BMS Faecal Microbiota Transplantation (FMT) was first recorded over 2000 years ago for the treatment of severe diarrhoea. FMT is an infusion of a faecal suspension from a healthy individual to the GI tract of a recipient patient, in order to treat a disorder associated with an alteration of gut microbiota. It is proposed that Ulcerative Colitis (UC) is caused by a bacteria or group of bacteria within the microbiome interacting with genetically susceptible individuals to cause chronic relapsing inflammation of the colon. Increasing evidence has shown frozen faecal infusions from unrelated donors are as effective as related donors which has provided an opportunity for a better standardised approach for donor selection, screening, and treatment preparation. Conference Paper/Proceeding/Abstract Falk Foundation Symposium 217: West Meets East: Functional Meets Organic in Gastrointestinal Diseases 29 11 2019 2019-11-29 http://www.falk-foundation-symposia.org/symposia-and-workshops/2019/?L=1 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University 2020-07-08T15:05:40.6537039 2020-01-27T11:04:34.6940970 Matthew Hitchings 0000-0002-5527-4709 1 Andrew Cunningham 2 Sue Chandler 3 Dean Harris 0000-0003-2673-8946 4
title The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
spellingShingle The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
Matthew Hitchings
Dean Harris
title_short The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
title_full The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
title_fullStr The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
title_full_unstemmed The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
title_sort The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD
author_id_str_mv be98847c72c14a731c4a6b7bc02b3bcf
731533890c5123febe4f65dffd369f7b
author_id_fullname_str_mv be98847c72c14a731c4a6b7bc02b3bcf_***_Matthew Hitchings
731533890c5123febe4f65dffd369f7b_***_Dean Harris
author Matthew Hitchings
Dean Harris
author2 Matthew Hitchings
Andrew Cunningham
Sue Chandler
Dean Harris
format Conference Paper/Proceeding/Abstract
container_title Falk Foundation Symposium 217: West Meets East: Functional Meets Organic in Gastrointestinal Diseases
publishDate 2019
institution Swansea University
url http://www.falk-foundation-symposia.org/symposia-and-workshops/2019/?L=1
document_store_str 0
active_str 0
description Faecal Microbiota Transplantation (FMT) was first recorded over 2000 years ago for the treatment of severe diarrhoea. FMT is an infusion of a faecal suspension from a healthy individual to the GI tract of a recipient patient, in order to treat a disorder associated with an alteration of gut microbiota. It is proposed that Ulcerative Colitis (UC) is caused by a bacteria or group of bacteria within the microbiome interacting with genetically susceptible individuals to cause chronic relapsing inflammation of the colon. Increasing evidence has shown frozen faecal infusions from unrelated donors are as effective as related donors which has provided an opportunity for a better standardised approach for donor selection, screening, and treatment preparation.
published_date 2019-11-29T04:06:16Z
_version_ 1763753461398110208
score 11.012678

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