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Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

Paola Oliva, Romeo Romagnoli, Stefano Manfredini, Andrea Brancale, Salvatore Ferla Orcid Logo, Ernest Hamel, Roberto Ronca, Federica Maccarinelli, Arianna Giacomini, Fatlum Rruga, Elena Mariotto, Giampietro Viola, Roberta Bortolozzi

European Journal of Medicinal Chemistry, Volume: 200, Start page: 112448

Swansea University Author: Salvatore Ferla Orcid Logo

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Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2020
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Keywords: Microtubules; Benzo[b]furan; In vivo activity; Inhibition tubulin assembly; Colchicine binding site
College: Faculty of Medicine, Health and Life Sciences
Start Page: 112448