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Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

Paola Oliva, Romeo Romagnoli, Stefano Manfredini, Andrea Brancale, Salvatore Ferla Orcid Logo, Ernest Hamel, Roberto Ronca, Federica Maccarinelli, Arianna Giacomini, Fatlum Rruga, Elena Mariotto, Giampietro Viola, Roberta Bortolozzi

European Journal of Medicinal Chemistry, Volume: 200, Start page: 112448

Swansea University Author: Salvatore Ferla Orcid Logo

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Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa55226
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first_indexed 2020-10-18T17:15:32Z
last_indexed 2020-11-25T04:12:01Z
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spelling 2020-11-24T17:09:26.3858158 v2 55226 2020-09-20 Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors d4c62248f510e3b221916989a7bbe6a6 0000-0002-5918-9237 Salvatore Ferla Salvatore Ferla true false 2020-09-20 PHAR Journal Article European Journal of Medicinal Chemistry 200 112448 Elsevier BV 0223-5234 Microtubules; Benzo[b]furan; In vivo activity; Inhibition tubulin assembly; Colchicine binding site 15 8 2020 2020-08-15 10.1016/j.ejmech.2020.112448 http://orca.cf.ac.uk/131812/ COLLEGE NANME Pharmacy COLLEGE CODE PHAR Swansea University 2020-11-24T17:09:26.3858158 2020-09-20T14:09:06.9904500 Swansea University Medical School Swansea University Medical School Paola Oliva 1 Romeo Romagnoli 2 Stefano Manfredini 3 Andrea Brancale 4 Salvatore Ferla 0000-0002-5918-9237 5 Ernest Hamel 6 Roberto Ronca 7 Federica Maccarinelli 8 Arianna Giacomini 9 Fatlum Rruga 10 Elena Mariotto 11 Giampietro Viola 12 Roberta Bortolozzi 13
title Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
spellingShingle Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
Salvatore Ferla
title_short Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
title_full Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
title_fullStr Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
title_full_unstemmed Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
title_sort Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
author_id_str_mv d4c62248f510e3b221916989a7bbe6a6
author_id_fullname_str_mv d4c62248f510e3b221916989a7bbe6a6_***_Salvatore Ferla
author Salvatore Ferla
author2 Paola Oliva
Romeo Romagnoli
Stefano Manfredini
Andrea Brancale
Salvatore Ferla
Ernest Hamel
Roberto Ronca
Federica Maccarinelli
Arianna Giacomini
Fatlum Rruga
Elena Mariotto
Giampietro Viola
Roberta Bortolozzi
format Journal article
container_title European Journal of Medicinal Chemistry
container_volume 200
container_start_page 112448
publishDate 2020
institution Swansea University
issn 0223-5234
doi_str_mv 10.1016/j.ejmech.2020.112448
publisher Elsevier BV
college_str Swansea University Medical School
hierarchytype
hierarchy_top_id swanseauniversitymedicalschool
hierarchy_top_title Swansea University Medical School
hierarchy_parent_id swanseauniversitymedicalschool
hierarchy_parent_title Swansea University Medical School
department_str Swansea University Medical School{{{_:::_}}}Swansea University Medical School{{{_:::_}}}Swansea University Medical School
url http://orca.cf.ac.uk/131812/
document_store_str 0
active_str 0
published_date 2020-08-15T04:10:12Z
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