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2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition

Romeo Romagnoli, Maria Kimatrai Salvador, Santiago Schiaffino Ortega, Pier Giovanni Baraldi, Paola Oliva, Stefania Baraldi, Luisa Carlota Lopez-Cara, Andrea Brancale, Salvatore Ferla Orcid Logo, Ernest Hamel, Jan Balzarini, Sandra Liekens, Elena Mattiuzzo, Giuseppe Basso, Giampietro Viola

European Journal of Medicinal Chemistry, Volume: 143, Pages: 683 - 698

Swansea University Author: Salvatore Ferla Orcid Logo

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Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2018
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa55477
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Keywords: Microtubule; Tubulin polymerization inhibitors; Antiproliferative agents; Colchicine site; Structure-activity relationship
College: Faculty of Medicine, Health and Life Sciences
Start Page: 683
End Page: 698