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Molecular hierarchical release using hydrogenated graphene origami under electric field

Shuai Luo, Adesola Ademiloye Orcid Logo, Zhengtian Wu, Yang Zhang

Materials Science in Semiconductor Processing, Volume: 131, Start page: 105844

Swansea University Author: Adesola Ademiloye Orcid Logo

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DOI (Published version): 10.1016/j.mssp.2021.105844

Abstract

In recent years, drug delivery has progressively become one of the main research areas in the field of biomedicine. However, the graded drug release remains a serious challenge at the nano-scales. Herein, we successfully simulated the graded release of C60 and C180 from the graphene box inspired by...

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Published in: Materials Science in Semiconductor Processing
ISSN: 1369-8001
Published: Elsevier BV 2021
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URI: https://cronfa.swan.ac.uk/Record/cronfa56694
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spelling 2021-12-02T11:22:18.3704566 v2 56694 2021-04-19 Molecular hierarchical release using hydrogenated graphene origami under electric field e37960ed89a7e3eaeba2201762626594 0000-0002-9741-6488 Adesola Ademiloye Adesola Ademiloye true false 2021-04-19 MEDE In recent years, drug delivery has progressively become one of the main research areas in the field of biomedicine. However, the graded drug release remains a serious challenge at the nano-scales. Herein, we successfully simulated the graded release of C60 and C180 from the graphene box inspired by the origami technique under the control of an external electric field via molecular dynamics (MD) simulations. Our results provide a feasible scheme for hierarchical drug delivery at the nano-scales. The graphene origami was generated through the folding of graphene guided by its creases which were created by combining carbon atoms with hydrogen atoms and transforming sp2 to sp3 bonds at the combination line. We can construct complex graphene origami by designing reasonable hydrogen atoms distribution on graphene. This provides a simple and practicable program for designing complex graphene-based nanodevices for drug delivery. Journal Article Materials Science in Semiconductor Processing 131 105844 Elsevier BV 1369-8001 Graphene, Origami, Electric field, Self-folding, Drug delivery, MD simulation 15 8 2021 2021-08-15 10.1016/j.mssp.2021.105844 COLLEGE NANME Biomedical Engineering COLLEGE CODE MEDE Swansea University 2021-12-02T11:22:18.3704566 2021-04-19T14:57:38.8674900 Faculty of Science and Engineering School of Engineering and Applied Sciences - Biomedical Engineering Shuai Luo 1 Adesola Ademiloye 0000-0002-9741-6488 2 Zhengtian Wu 3 Yang Zhang 4 56694__19685__06e54519a16e413089e6a0b2bccd7d71.pdf 56694.pdf 2021-04-19T14:59:25.1041553 Output 1814927 application/pdf Accepted Manuscript true 2022-04-26T00:00:00.0000000 ©2021 All rights reserved. All article content, except where otherwise noted, is licensed under a Creative Commons Attribution Non-Commercial No Derivatives License (CC-BY-NC-ND) true eng http://creativecommons.org/licenses/by-nc-nd/4.0/
title Molecular hierarchical release using hydrogenated graphene origami under electric field
spellingShingle Molecular hierarchical release using hydrogenated graphene origami under electric field
Adesola Ademiloye
title_short Molecular hierarchical release using hydrogenated graphene origami under electric field
title_full Molecular hierarchical release using hydrogenated graphene origami under electric field
title_fullStr Molecular hierarchical release using hydrogenated graphene origami under electric field
title_full_unstemmed Molecular hierarchical release using hydrogenated graphene origami under electric field
title_sort Molecular hierarchical release using hydrogenated graphene origami under electric field
author_id_str_mv e37960ed89a7e3eaeba2201762626594
author_id_fullname_str_mv e37960ed89a7e3eaeba2201762626594_***_Adesola Ademiloye
author Adesola Ademiloye
author2 Shuai Luo
Adesola Ademiloye
Zhengtian Wu
Yang Zhang
format Journal article
container_title Materials Science in Semiconductor Processing
container_volume 131
container_start_page 105844
publishDate 2021
institution Swansea University
issn 1369-8001
doi_str_mv 10.1016/j.mssp.2021.105844
publisher Elsevier BV
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Biomedical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Biomedical Engineering
document_store_str 1
active_str 0
description In recent years, drug delivery has progressively become one of the main research areas in the field of biomedicine. However, the graded drug release remains a serious challenge at the nano-scales. Herein, we successfully simulated the graded release of C60 and C180 from the graphene box inspired by the origami technique under the control of an external electric field via molecular dynamics (MD) simulations. Our results provide a feasible scheme for hierarchical drug delivery at the nano-scales. The graphene origami was generated through the folding of graphene guided by its creases which were created by combining carbon atoms with hydrogen atoms and transforming sp2 to sp3 bonds at the combination line. We can construct complex graphene origami by designing reasonable hydrogen atoms distribution on graphene. This provides a simple and practicable program for designing complex graphene-based nanodevices for drug delivery.
published_date 2021-08-15T04:11:50Z
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score 11.035634

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