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The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments
Frontiers in Physiology, Volume: 12
Swansea University Author: Feihu Zhao
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© 2021 Qi, Zhu, Qian, Xu, He and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)Download (4.26MB)
DOI (Published version): 10.3389/fphys.2021.734565
At present, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery stenosis. However, in case post-dilation of the stent is needed, the tip of the commonly used post-dilation balloon catheter cannot always pass through the stent smoothly, especially when it is si...
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At present, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery stenosis. However, in case post-dilation of the stent is needed, the tip of the commonly used post-dilation balloon catheter cannot always pass through the stent smoothly, especially when it is situated in the curved part of the vessel. To improve the performance of traditional post-dilation balloon catheter, a preliminary design of a novel catheter with a spherical-tip is proposed. Since the performance of this spherical-tip catheter is still unclear, in this study, finite element analysis (FEA) and experimental validation of blood vessel with different curvature radii were performed to test and evaluate the performance of the spherical-tip catheter design. The comparative results between the two types of catheters demonstrate that in the simulated post-dilation process, the spherical-tip catheter is easier to pass through the stent placed in the curved vessel without the deformation of the stent strut, and can theoretically reduce the operation time and improve the safety of the operation. Furthermore, the strong consistency between simulation and experiment indicates that the finite element (FE) model can be a helpful tool for future optimization and evaluation of novel catheters, so as to save time and budget in product development and reduce/replace animal studies.
Physiology, post-dilation, spherical-tip catheter, finite element analysis, percutaneous coronary intervention, finite element model
Faculty of Science and Engineering
National Key Research and Development Program of China; National Natural Science Foundation of China; Fundamental Research Funds for the Central Universities; Open Grant by National
Health Commission Key Laboratory of Assisted Circulation (Sun Yat-sen University)