Journal article 631 views 88 downloads
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments
Frontiers in Physiology, Volume: 12
Swansea University Author:
Feihu Zhao
-
PDF | Version of Record
© 2021 Qi, Zhu, Qian, Xu, He and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)
Download (4.26MB)
DOI (Published version): 10.3389/fphys.2021.734565
Abstract
At present, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery stenosis. However, in case post-dilation of the stent is needed, the tip of the commonly used post-dilation balloon catheter cannot always pass through the stent smoothly, especially when it is si...
Published in: | Frontiers in Physiology |
---|---|
ISSN: | 1664-042X |
Published: |
Frontiers Media SA
2021
|
Online Access: |
Check full text
|
URI: | https://cronfa.swan.ac.uk/Record/cronfa57927 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
first_indexed |
2021-09-27T10:25:41Z |
---|---|
last_indexed |
2021-09-29T03:22:17Z |
id |
cronfa57927 |
recordtype |
SURis |
fullrecord |
<?xml version="1.0"?><rfc1807><datestamp>2021-09-28T16:48:12.6974408</datestamp><bib-version>v2</bib-version><id>57927</id><entry>2021-09-16</entry><title>The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments</title><swanseaauthors><author><sid>1c6e79b6edd08c88a8d17a241cd78630</sid><ORCID>0000-0003-0515-6808</ORCID><firstname>Feihu</firstname><surname>Zhao</surname><name>Feihu Zhao</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2021-09-16</date><deptcode>MEDE</deptcode><abstract>At present, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery stenosis. However, in case post-dilation of the stent is needed, the tip of the commonly used post-dilation balloon catheter cannot always pass through the stent smoothly, especially when it is situated in the curved part of the vessel. To improve the performance of traditional post-dilation balloon catheter, a preliminary design of a novel catheter with a spherical-tip is proposed. Since the performance of this spherical-tip catheter is still unclear, in this study, finite element analysis (FEA) and experimental validation of blood vessel with different curvature radii were performed to test and evaluate the performance of the spherical-tip catheter design. The comparative results between the two types of catheters demonstrate that in the simulated post-dilation process, the spherical-tip catheter is easier to pass through the stent placed in the curved vessel without the deformation of the stent strut, and can theoretically reduce the operation time and improve the safety of the operation. Furthermore, the strong consistency between simulation and experiment indicates that the finite element (FE) model can be a helpful tool for future optimization and evaluation of novel catheters, so as to save time and budget in product development and reduce/replace animal studies.</abstract><type>Journal Article</type><journal>Frontiers in Physiology</journal><volume>12</volume><journalNumber/><paginationStart/><paginationEnd/><publisher>Frontiers Media SA</publisher><placeOfPublication/><isbnPrint/><isbnElectronic/><issnPrint/><issnElectronic>1664-042X</issnElectronic><keywords>Physiology, post-dilation, spherical-tip catheter, finite element analysis, percutaneous coronary intervention, finite element model</keywords><publishedDay>31</publishedDay><publishedMonth>8</publishedMonth><publishedYear>2021</publishedYear><publishedDate>2021-08-31</publishedDate><doi>10.3389/fphys.2021.734565</doi><url/><notes/><college>COLLEGE NANME</college><department>Biomedical Engineering</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>MEDE</DepartmentCode><institution>Swansea University</institution><apcterm/><funders>National Key Research and Development Program of China; National Natural Science Foundation of China; Fundamental Research Funds for the Central Universities; Open Grant by National
Health Commission Key Laboratory of Assisted Circulation (Sun Yat-sen University)</funders><projectreference>2020YFC2004400; No. 61773110; No. N2119008; No. cvclab201901</projectreference><lastEdited>2021-09-28T16:48:12.6974408</lastEdited><Created>2021-09-16T16:16:11.0793057</Created><path><level id="1">Faculty of Science and Engineering</level><level id="2">School of Engineering and Applied Sciences - Biomedical Engineering</level></path><authors><author><firstname>Lin</firstname><surname>Qi</surname><order>1</order></author><author><firstname>Wenbo</firstname><surname>Zhu</surname><order>2</order></author><author><firstname>Wei</firstname><surname>Qian</surname><order>3</order></author><author><firstname>Lisheng</firstname><surname>Xu</surname><order>4</order></author><author><firstname>Ying</firstname><surname>He</surname><order>5</order></author><author><firstname>Feihu</firstname><surname>Zhao</surname><orcid>0000-0003-0515-6808</orcid><order>6</order></author></authors><documents><document><filename>57927__20894__9c1897ac38d5441382858325daeded28.pdf</filename><originalFilename>fphys-12-734565.pdf</originalFilename><uploaded>2021-09-16T16:16:11.0789872</uploaded><type>Output</type><contentLength>4462722</contentLength><contentType>application/pdf</contentType><version>Version of Record</version><cronfaStatus>true</cronfaStatus><documentNotes>© 2021 Qi, Zhu, Qian, Xu, He and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)</documentNotes><copyrightCorrect>true</copyrightCorrect><language>eng</language><licence>http://creativecommons.org/licenses/by/4.0/</licence></document></documents><OutputDurs/></rfc1807> |
spelling |
2021-09-28T16:48:12.6974408 v2 57927 2021-09-16 The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments 1c6e79b6edd08c88a8d17a241cd78630 0000-0003-0515-6808 Feihu Zhao Feihu Zhao true false 2021-09-16 MEDE At present, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery stenosis. However, in case post-dilation of the stent is needed, the tip of the commonly used post-dilation balloon catheter cannot always pass through the stent smoothly, especially when it is situated in the curved part of the vessel. To improve the performance of traditional post-dilation balloon catheter, a preliminary design of a novel catheter with a spherical-tip is proposed. Since the performance of this spherical-tip catheter is still unclear, in this study, finite element analysis (FEA) and experimental validation of blood vessel with different curvature radii were performed to test and evaluate the performance of the spherical-tip catheter design. The comparative results between the two types of catheters demonstrate that in the simulated post-dilation process, the spherical-tip catheter is easier to pass through the stent placed in the curved vessel without the deformation of the stent strut, and can theoretically reduce the operation time and improve the safety of the operation. Furthermore, the strong consistency between simulation and experiment indicates that the finite element (FE) model can be a helpful tool for future optimization and evaluation of novel catheters, so as to save time and budget in product development and reduce/replace animal studies. Journal Article Frontiers in Physiology 12 Frontiers Media SA 1664-042X Physiology, post-dilation, spherical-tip catheter, finite element analysis, percutaneous coronary intervention, finite element model 31 8 2021 2021-08-31 10.3389/fphys.2021.734565 COLLEGE NANME Biomedical Engineering COLLEGE CODE MEDE Swansea University National Key Research and Development Program of China; National Natural Science Foundation of China; Fundamental Research Funds for the Central Universities; Open Grant by National Health Commission Key Laboratory of Assisted Circulation (Sun Yat-sen University) 2020YFC2004400; No. 61773110; No. N2119008; No. cvclab201901 2021-09-28T16:48:12.6974408 2021-09-16T16:16:11.0793057 Faculty of Science and Engineering School of Engineering and Applied Sciences - Biomedical Engineering Lin Qi 1 Wenbo Zhu 2 Wei Qian 3 Lisheng Xu 4 Ying He 5 Feihu Zhao 0000-0003-0515-6808 6 57927__20894__9c1897ac38d5441382858325daeded28.pdf fphys-12-734565.pdf 2021-09-16T16:16:11.0789872 Output 4462722 application/pdf Version of Record true © 2021 Qi, Zhu, Qian, Xu, He and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) true eng http://creativecommons.org/licenses/by/4.0/ |
title |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments |
spellingShingle |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments Feihu Zhao |
title_short |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments |
title_full |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments |
title_fullStr |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments |
title_full_unstemmed |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments |
title_sort |
The Performance of a Spherical-tip Catheter for Stent Post-dilation: Finite Element Analysis and Experiments |
author_id_str_mv |
1c6e79b6edd08c88a8d17a241cd78630 |
author_id_fullname_str_mv |
1c6e79b6edd08c88a8d17a241cd78630_***_Feihu Zhao |
author |
Feihu Zhao |
author2 |
Lin Qi Wenbo Zhu Wei Qian Lisheng Xu Ying He Feihu Zhao |
format |
Journal article |
container_title |
Frontiers in Physiology |
container_volume |
12 |
publishDate |
2021 |
institution |
Swansea University |
issn |
1664-042X |
doi_str_mv |
10.3389/fphys.2021.734565 |
publisher |
Frontiers Media SA |
college_str |
Faculty of Science and Engineering |
hierarchytype |
|
hierarchy_top_id |
facultyofscienceandengineering |
hierarchy_top_title |
Faculty of Science and Engineering |
hierarchy_parent_id |
facultyofscienceandengineering |
hierarchy_parent_title |
Faculty of Science and Engineering |
department_str |
School of Engineering and Applied Sciences - Biomedical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Biomedical Engineering |
document_store_str |
1 |
active_str |
0 |
description |
At present, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery stenosis. However, in case post-dilation of the stent is needed, the tip of the commonly used post-dilation balloon catheter cannot always pass through the stent smoothly, especially when it is situated in the curved part of the vessel. To improve the performance of traditional post-dilation balloon catheter, a preliminary design of a novel catheter with a spherical-tip is proposed. Since the performance of this spherical-tip catheter is still unclear, in this study, finite element analysis (FEA) and experimental validation of blood vessel with different curvature radii were performed to test and evaluate the performance of the spherical-tip catheter design. The comparative results between the two types of catheters demonstrate that in the simulated post-dilation process, the spherical-tip catheter is easier to pass through the stent placed in the curved vessel without the deformation of the stent strut, and can theoretically reduce the operation time and improve the safety of the operation. Furthermore, the strong consistency between simulation and experiment indicates that the finite element (FE) model can be a helpful tool for future optimization and evaluation of novel catheters, so as to save time and budget in product development and reduce/replace animal studies. |
published_date |
2021-08-31T04:14:02Z |
_version_ |
1763753949521772544 |
score |
11.021648 |