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Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
Progress in Organic Coatings, Volume: 172, Start page: 107135
Swansea University Authors:
Calvin Richards, Geraint Williams
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DOI (Published version): 10.1016/j.porgcoat.2022.107135
Abstract
Viruses such as SARS-CoV-2 can remain viable on solid surfaces for up to one week, hence fomites are a potential route of exposure to infectious virus. Copper has well documented antiviral properties that could limit this problem, however practical deployment of copper surfaces has been limited due...
Published in: | Progress in Organic Coatings |
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ISSN: | 0300-9440 |
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Elsevier BV
2022
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URI: | https://cronfa.swan.ac.uk/Record/cronfa60872 |
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2022-09-08T14:02:50.1024942 v2 60872 2022-08-23 Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments fba04fac258816964c5a4ba702b025e9 Calvin Richards Calvin Richards true false 0d8fc8d44e2a3c88ce61832f66f20d82 0000-0002-3399-5142 Geraint Williams Geraint Williams true false 2022-08-23 MTLS Viruses such as SARS-CoV-2 can remain viable on solid surfaces for up to one week, hence fomites are a potential route of exposure to infectious virus. Copper has well documented antiviral properties that could limit this problem, however practical deployment of copper surfaces has been limited due to the associated costs and the incompatibility of copper metal in specific environments and conditions. We therefore developed an organic coating containing an intelligent-release Cu2+ pigment based on a cation exchange resin. Organic coatings containing a 50 % weight or higher loading of smart-release pigment were capable of completely inactivating (>6 log reduction in titre) SARS-CoV-2 within 4 h of incubation. Importantly these organic coatings demonstrated a significantly enhanced ability to inactivate SARS-CoV-2 compared to metallic copper and un-pigmented material. Furthermore, the presence of contaminating proteins inhibited the antiviral activity of metallic copper, but the intelligent-release Cu2+ pigment was unaffected. The approach of using a very basic paint system, based on a polymer binder embedded with “smart release” pigment containing an anti-viral agent which is liberated by ion-exchange, holds significant promise as a cost effective and rapidly deployed coating to confer virus inactivating capability to high touch surfaces. Journal Article Progress in Organic Coatings 172 107135 Elsevier BV 0300-9440 SARS-CoV-2, Organic coating, Anti-viral, Copper, Covid19, Smart-release 1 11 2022 2022-11-01 10.1016/j.porgcoat.2022.107135 COLLEGE NANME Materials Science and Engineering COLLEGE CODE MTLS Swansea University This work was supported by funding from the EPSRC (EP/N020863/1), MRC (MR/V028448/1, MR/S00971X/1), and Accelerate Wales. 2022-09-08T14:02:50.1024942 2022-08-23T15:00:06.1394926 Faculty of Science and Engineering School of Engineering and Applied Sciences - Materials Science and Engineering Zack Saud 1 Calvin Richards 2 Geraint Williams 0000-0002-3399-5142 3 Richard J. Stanton 4 60872__24995__472801c39d88480ead0a9458d9073de7.pdf 60872.pdf 2022-08-23T15:03:01.1832319 Output 2373377 application/pdf Version of Record true © 2022 The Authors. This is an open access article under the CC BY license true eng http://creativecommons.org/licenses/by/4.0/ |
title |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments |
spellingShingle |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments Calvin Richards Geraint Williams |
title_short |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments |
title_full |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments |
title_fullStr |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments |
title_full_unstemmed |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments |
title_sort |
Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments |
author_id_str_mv |
fba04fac258816964c5a4ba702b025e9 0d8fc8d44e2a3c88ce61832f66f20d82 |
author_id_fullname_str_mv |
fba04fac258816964c5a4ba702b025e9_***_Calvin Richards 0d8fc8d44e2a3c88ce61832f66f20d82_***_Geraint Williams |
author |
Calvin Richards Geraint Williams |
author2 |
Zack Saud Calvin Richards Geraint Williams Richard J. Stanton |
format |
Journal article |
container_title |
Progress in Organic Coatings |
container_volume |
172 |
container_start_page |
107135 |
publishDate |
2022 |
institution |
Swansea University |
issn |
0300-9440 |
doi_str_mv |
10.1016/j.porgcoat.2022.107135 |
publisher |
Elsevier BV |
college_str |
Faculty of Science and Engineering |
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facultyofscienceandengineering |
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Faculty of Science and Engineering |
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facultyofscienceandengineering |
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Faculty of Science and Engineering |
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School of Engineering and Applied Sciences - Materials Science and Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Materials Science and Engineering |
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description |
Viruses such as SARS-CoV-2 can remain viable on solid surfaces for up to one week, hence fomites are a potential route of exposure to infectious virus. Copper has well documented antiviral properties that could limit this problem, however practical deployment of copper surfaces has been limited due to the associated costs and the incompatibility of copper metal in specific environments and conditions. We therefore developed an organic coating containing an intelligent-release Cu2+ pigment based on a cation exchange resin. Organic coatings containing a 50 % weight or higher loading of smart-release pigment were capable of completely inactivating (>6 log reduction in titre) SARS-CoV-2 within 4 h of incubation. Importantly these organic coatings demonstrated a significantly enhanced ability to inactivate SARS-CoV-2 compared to metallic copper and un-pigmented material. Furthermore, the presence of contaminating proteins inhibited the antiviral activity of metallic copper, but the intelligent-release Cu2+ pigment was unaffected. The approach of using a very basic paint system, based on a polymer binder embedded with “smart release” pigment containing an anti-viral agent which is liberated by ion-exchange, holds significant promise as a cost effective and rapidly deployed coating to confer virus inactivating capability to high touch surfaces. |
published_date |
2022-11-01T04:19:21Z |
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1763754284130762752 |
score |
11.021648 |