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Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments

Zack Saud, Calvin Richards, Geraint Williams Orcid Logo, Richard J. Stanton

Progress in Organic Coatings, Volume: 172, Start page: 107135

Swansea University Authors: Calvin Richards, Geraint Williams Orcid Logo

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DOI (Published version): 10.1016/j.porgcoat.2022.107135

Abstract

Viruses such as SARS-CoV-2 can remain viable on solid surfaces for up to one week, hence fomites are a potential route of exposure to infectious virus. Copper has well documented antiviral properties that could limit this problem, however practical deployment of copper surfaces has been limited due...

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Published in: Progress in Organic Coatings
ISSN: 0300-9440
Published: Elsevier BV 2022
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URI: https://cronfa.swan.ac.uk/Record/cronfa60872
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first_indexed 2022-08-23T14:03:09Z
last_indexed 2023-01-13T19:21:19Z
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spelling 2022-09-08T14:02:50.1024942 v2 60872 2022-08-23 Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments fba04fac258816964c5a4ba702b025e9 Calvin Richards Calvin Richards true false 0d8fc8d44e2a3c88ce61832f66f20d82 0000-0002-3399-5142 Geraint Williams Geraint Williams true false 2022-08-23 MTLS Viruses such as SARS-CoV-2 can remain viable on solid surfaces for up to one week, hence fomites are a potential route of exposure to infectious virus. Copper has well documented antiviral properties that could limit this problem, however practical deployment of copper surfaces has been limited due to the associated costs and the incompatibility of copper metal in specific environments and conditions. We therefore developed an organic coating containing an intelligent-release Cu2+ pigment based on a cation exchange resin. Organic coatings containing a 50 % weight or higher loading of smart-release pigment were capable of completely inactivating (>6 log reduction in titre) SARS-CoV-2 within 4 h of incubation. Importantly these organic coatings demonstrated a significantly enhanced ability to inactivate SARS-CoV-2 compared to metallic copper and un-pigmented material. Furthermore, the presence of contaminating proteins inhibited the antiviral activity of metallic copper, but the intelligent-release Cu2+ pigment was unaffected. The approach of using a very basic paint system, based on a polymer binder embedded with “smart release” pigment containing an anti-viral agent which is liberated by ion-exchange, holds significant promise as a cost effective and rapidly deployed coating to confer virus inactivating capability to high touch surfaces. Journal Article Progress in Organic Coatings 172 107135 Elsevier BV 0300-9440 SARS-CoV-2, Organic coating, Anti-viral, Copper, Covid19, Smart-release 1 11 2022 2022-11-01 10.1016/j.porgcoat.2022.107135 COLLEGE NANME Materials Science and Engineering COLLEGE CODE MTLS Swansea University This work was supported by funding from the EPSRC (EP/N020863/1), MRC (MR/V028448/1, MR/S00971X/1), and Accelerate Wales. 2022-09-08T14:02:50.1024942 2022-08-23T15:00:06.1394926 Faculty of Science and Engineering School of Engineering and Applied Sciences - Materials Science and Engineering Zack Saud 1 Calvin Richards 2 Geraint Williams 0000-0002-3399-5142 3 Richard J. Stanton 4 60872__24995__472801c39d88480ead0a9458d9073de7.pdf 60872.pdf 2022-08-23T15:03:01.1832319 Output 2373377 application/pdf Version of Record true © 2022 The Authors. This is an open access article under the CC BY license true eng http://creativecommons.org/licenses/by/4.0/
title Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
spellingShingle Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
Calvin Richards
Geraint Williams
title_short Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
title_full Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
title_fullStr Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
title_full_unstemmed Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
title_sort Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments
author_id_str_mv fba04fac258816964c5a4ba702b025e9
0d8fc8d44e2a3c88ce61832f66f20d82
author_id_fullname_str_mv fba04fac258816964c5a4ba702b025e9_***_Calvin Richards
0d8fc8d44e2a3c88ce61832f66f20d82_***_Geraint Williams
author Calvin Richards
Geraint Williams
author2 Zack Saud
Calvin Richards
Geraint Williams
Richard J. Stanton
format Journal article
container_title Progress in Organic Coatings
container_volume 172
container_start_page 107135
publishDate 2022
institution Swansea University
issn 0300-9440
doi_str_mv 10.1016/j.porgcoat.2022.107135
publisher Elsevier BV
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Materials Science and Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Materials Science and Engineering
document_store_str 1
active_str 0
description Viruses such as SARS-CoV-2 can remain viable on solid surfaces for up to one week, hence fomites are a potential route of exposure to infectious virus. Copper has well documented antiviral properties that could limit this problem, however practical deployment of copper surfaces has been limited due to the associated costs and the incompatibility of copper metal in specific environments and conditions. We therefore developed an organic coating containing an intelligent-release Cu2+ pigment based on a cation exchange resin. Organic coatings containing a 50 % weight or higher loading of smart-release pigment were capable of completely inactivating (>6 log reduction in titre) SARS-CoV-2 within 4 h of incubation. Importantly these organic coatings demonstrated a significantly enhanced ability to inactivate SARS-CoV-2 compared to metallic copper and un-pigmented material. Furthermore, the presence of contaminating proteins inhibited the antiviral activity of metallic copper, but the intelligent-release Cu2+ pigment was unaffected. The approach of using a very basic paint system, based on a polymer binder embedded with “smart release” pigment containing an anti-viral agent which is liberated by ion-exchange, holds significant promise as a cost effective and rapidly deployed coating to confer virus inactivating capability to high touch surfaces.
published_date 2022-11-01T04:19:21Z
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score 11.035655

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