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Transient changes during microwave ablation simulation : a comparative shape analysis

DALE KERNOT, Jimmy Yang, Nicholas Williams, Tudor Thomas, Paul Ledger, Hari Arora Orcid Logo, Raoul van Loon Orcid Logo

Biomechanics and Modeling in Mechanobiology, Volume: 22

Swansea University Authors: DALE KERNOT, Hari Arora Orcid Logo, Raoul van Loon Orcid Logo

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Abstract

Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region. Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption...

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Published in: Biomechanics and Modeling in Mechanobiology
ISSN: 1617-7959 1617-7940
Published: Springer Science and Business Media LLC 2022
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa61532
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Abstract: Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region. Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption rate fields throughout the course of simulated treatment with different probe concepts. Here, an axisymmetric geometry of a probe embedded within a tissue material is created, solving coupled electromagnetic and bioheat equations using the finite element method, utilizing hp discretisation with the NGSolve library. Results show dynamic changes across all metrics, with different responses from different probe concepts. The sleeve probe yielded the most circular specific absorption rate pattern with circularity of 0.81 initially but suffered the largest reduction throughout ablation. Similarly, reflection coefficients differ drastically from their initial values, with the sleeve probe again experiencing the largest change, suggesting that it is the most sensitive the changes in the tissue dielectric properties in these select probe designs. These collective characteristic observations highlight the need to consider dielectric property changes and probe specific responses during the design cycle.
Keywords: Microwave ablation (MWA); Bioheat; Hyperthermal treatment; Numerical simulation; Shape analysis; Temperature sensitivity
College: Faculty of Science and Engineering
Funders: This work is part-funded by the European Social Fund through the European Union’s Convergence programme administered by the Welsh Government, and Olympus Surgical Technologies Europe. I would like to acknowledge the Engineering and Physical Sciences Research Council for their support through grant EP/V009028/1. Author DK received research support from Olympus Surgical Technologies Europe.