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Cognitive and Neuropsychiatric Impairment in Dystonia

Grace Bailey Orcid Logo, Eva Martin, Kathryn J. Peall Orcid Logo

Current Neurology and Neuroscience Reports, Volume: 22, Issue: 11, Pages: 699 - 708

Swansea University Author: Grace Bailey Orcid Logo

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Abstract

Purpose of ReviewTo review recent literature evaluating psychiatric and cognitive symptoms in dystonia, the two non-motor symptom groups most frequently evaluated in dystonia research and recognised in clinical practice.Recent FindingsRecent work has embedded clinical recognition of psychiatric symp...

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Published in: Current Neurology and Neuroscience Reports
ISSN: 1528-4042 1534-6293
Published: Springer Science and Business Media LLC 2022
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa66535
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Abstract: Purpose of ReviewTo review recent literature evaluating psychiatric and cognitive symptoms in dystonia, the two non-motor symptom groups most frequently evaluated in dystonia research and recognised in clinical practice.Recent FindingsRecent work has embedded clinical recognition of psychiatric symptoms in dystonia, with depressive and anxiety-related symptoms routinely observed to be the most common. Less explored symptoms, such as self-harm, suicidal ideation, and substance abuse, represent newer areas of investigation, with initial work suggesting higher rates than the background population. Investigation of cognitive function has provided less consistent results, both within individual dystonia subtypes and across the spectrum of dystonias, partly reflecting the heterogeneity in approaches to assessment. However, recent work indicates impairments of higher cognitive function, e.g. social cognition, and disrupted visual and auditory sensory processing.SummaryDystonia demonstrates psychiatric and cognitive symptom heterogeneity, with further work needed to recognise endophenotypes and improve diagnostic accuracy, symptom recognition, and management.
Keywords: Dystonia; Cognition; Psychiatric disorders; Non-motor symptoms
College: Faculty of Medicine, Health and Life Sciences
Funders: GAB is funded by a KESS2, European Social Fund and Cardiff University PhD Studentship. KJP is funded by an MRC Clinician-Scientist Fellowship (MR/P008593/1).
Issue: 11
Start Page: 699
End Page: 708