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Effect of home‐based exercise with or without a Mediterranean‐style diet on adiposity markers in postmenopausal women: A randomized‐control trial

Abbi Tan, Gareth Dunseath Orcid Logo, Becky Thomas Orcid Logo, Sarah Prior Orcid Logo, Richard Bracken Orcid Logo, Rachel Churm Orcid Logo

Physiological Reports, Volume: 13, Issue: 3, Start page: e70239

Swansea University Authors: Abbi Tan, Gareth Dunseath Orcid Logo, Becky Thomas Orcid Logo, Sarah Prior Orcid Logo, Richard Bracken Orcid Logo, Rachel Churm Orcid Logo

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DOI (Published version): 10.14814/phy2.70239

Abstract

Advancing age and estrogen deficiency increases susceptibility of post-menopausal women (PMW) to abdominal obesity and manifestation of cardiometabolic disease. There is limited evidence on the effect of lifestyle interventions on adiposity markers within at-risk PMW. Therefore, this study aims to e...

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Published in: Physiological Reports
ISSN: 2051-817X
Published: Wiley 2025
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URI: https://cronfa.swan.ac.uk/Record/cronfa68796
Abstract: Advancing age and estrogen deficiency increases susceptibility of post-menopausal women (PMW) to abdominal obesity and manifestation of cardiometabolic disease. There is limited evidence on the effect of lifestyle interventions on adiposity markers within at-risk PMW. Therefore, this study aims to evaluates an 8-weeks of home-based, equipment-free, interval training (HEFIT) with or without Mediterranean-style diet (MD) on adiposity markers in physically inactive, postmenopausal women with overweight/obesity. Thirty PMW (56.7 ± 3.9 years, BMI: 30.5 ± 5.2 kg/m2) were randomly assigned to three groups: (i) Ex; HEFIT thrice weekly/week, (ii) EX + MD, or (iii) CTL; control. Visceral Adiposity Index (VAI), body weight, BMI, waist and hip circumference (WC; HC), visceral adipose tissue (VAT), total body fat percentage, leptin, and adiponectin were determined pre- and post-8-week intervention. There was no significant between group effect on VAI. Compared to CTL, a significant between group reduction was seen in weight, BMI, and WC in both EX and EX+D (p < 0.05). Leptin and adiponectin remained unchanged in all groups (p > 0.05). Adherence rates were 85% and 96% for EX and EX+MD, respectively, and 80% of EX+D of participants had optimal adherence to diet. Concluding HEFIT with or without dietary changes could improve adiposity in overweight/obese postmenopausal women.
Keywords: abdominal obesity, adipokines, adipose tissue, cardiometabolic disease, cardiometabolic health, lifestyle intervention, postmenopausal women, women&apos;s health
College: Faculty of Science and Engineering
Funders: St David's Medical Foundation
Issue: 3
Start Page: e70239