Journal article 240 views 53 downloads
Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA
Lauren Murphy 
,
Jeanne Inchauspé ,
Giampiero Valenzano ,
Pamela Holland ,
Nikolaos Sousos ,
Hayley L. Belnoue-Davis,
Rong Li ,
Natalie J. Jooss ,
Camelia Benlabiod ,
Eleanor Murphy,
Zohar Etzioni ,
Emelie Shepherd,
Lucy Denly ,
Sujata Biswas ,
Lin Chen,
Jennifer O’Sullivan ,
Michael P. Rimmer ,
Abdullah O. Khan ,
Christina Simoglou Karali ,
Nadia Nasreddin ,
Ian S. Hitchcock ,
Milka Koupenova ,
Skirmantas Kriaucionis ,
Jim R. Hughes,
Eric O’Neill ,
Manu Vatish ,
Paul Rees ,
Simon Leedham ,
Michael Desborough ,
Adam J. Mead ,
Benjamin Schuster-Böckler ,
Christopher D. Gregory ,
Bethan Psaila
,
Jeanne Inchauspé ,
Giampiero Valenzano ,
Pamela Holland ,
Nikolaos Sousos ,
Hayley L. Belnoue-Davis,
Rong Li ,
Natalie J. Jooss ,
Camelia Benlabiod ,
Eleanor Murphy,
Zohar Etzioni ,
Emelie Shepherd,
Lucy Denly ,
Sujata Biswas ,
Lin Chen,
Jennifer O’Sullivan ,
Michael P. Rimmer ,
Abdullah O. Khan ,
Christina Simoglou Karali ,
Nadia Nasreddin ,
Ian S. Hitchcock ,
Milka Koupenova ,
Skirmantas Kriaucionis ,
Jim R. Hughes,
Eric O’Neill ,
Manu Vatish ,
Paul Rees ,
Simon Leedham ,
Michael Desborough ,
Adam J. Mead ,
Benjamin Schuster-Böckler ,
Christopher D. Gregory ,
Bethan Psaila
Science, Volume: 389, Issue: 6761
Swansea University Author:
Paul Rees
-
PDF | Accepted Manuscript
Author accepted manuscript document released under the terms of a Creative Commons CC-BY licence using the Swansea University Research Publications Policy (rights retention).
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DOI (Published version): 10.1126/science.adp3971
Abstract
Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA
| Published in: | Science |
|---|---|
| ISSN: | 0036-8075 1095-9203 |
| Published: |
American Association for the Advancement of Science (AAAS)
2025
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa70325 |
| College: |
Faculty of Science and Engineering |
|---|---|
| Funders: |
Funding was provided by Cancer Research UK Early Detection Project Grant EDDCPJT/100003 (B.P., C.D.G., P.R.); CRUK Advanced Clinical Scientist Fellowship C67633/A29034 (B.P.); Senior Fellowship RCCSCF-May24/100001 funded by Cancer Research UK in partnership with the Rosetrees Trust (B.P.); Ludwig Institute for Cancer Research Associate Member Program (B.P., B.S.-B.); Medical Research Council Grant MR/T04490X/1 (B.S.-B.); Kidani Memorial Trust (E.O.N.); CRUK Oxford Centre Clinical Research Training Fellowship C130623/A249471 (N.S.); and an unrestricted research grant from Emerson Health (now Yosemite) (B.P.). We also acknowledge support from the National Institute for Health Research (NIHR), Oxford Biomedical Research Centre (BRC), and CRUK Oxford Centre Grant CTRQQR-2021\100002. |
| Issue: |
6761 |