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Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols

William Griffiths Orcid Logo, Mohsen Ali Asgari, Yuqin Wang Orcid Logo

The Journal of Steroid Biochemistry and Molecular Biology, Start page: 106956

Swansea University Authors: William Griffiths Orcid Logo, Mohsen Ali Asgari, Yuqin Wang Orcid Logo

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DOI (Published version): 10.1016/j.jsbmb.2026.106956

Abstract

In this article we summarise the current mass spectrometry methods used for analysis of 7-ketocholesterol and related sterols, focusing on the advantages of the different methods with emphasis on pre-analytical and analytical precautions to avoid artefactual ex vivo formation of these oxysterols.

Published in: The Journal of Steroid Biochemistry and Molecular Biology
ISSN: 0960-0760
Published: Elsevier BV
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URI: https://cronfa.swan.ac.uk/Record/cronfa71464
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spelling 2026-02-19T11:58:49.7322534 v2 71464 2026-02-18 Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols 3316b1d1b524be1831790933eed1c26e 0000-0002-4129-6616 William Griffiths William Griffiths true false 58bf75dabf1a8c8d58eda61b305d3cfd Mohsen Ali Asgari Mohsen Ali Asgari true false c92729b58622f9fdf6a0e7d8f4ce5081 0000-0002-3063-3066 Yuqin Wang Yuqin Wang true false 2026-02-18 MEDS In this article we summarise the current mass spectrometry methods used for analysis of 7-ketocholesterol and related sterols, focusing on the advantages of the different methods with emphasis on pre-analytical and analytical precautions to avoid artefactual ex vivo formation of these oxysterols. Journal Article The Journal of Steroid Biochemistry and Molecular Biology 106956 Elsevier BV 0960-0760 0 0 0 0001-01-01 10.1016/j.jsbmb.2026.106956 https://doi.org/10.1016/j.jsbmb.2026.106956 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Not Required MRC, BBSRC MR/Y008057/1, BB/S019588/1 2026-02-19T11:58:49.7322534 2026-02-18T15:27:34.8488364 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Biomedical Science William Griffiths 0000-0002-4129-6616 1 Mohsen Ali Asgari 2 Yuqin Wang 0000-0002-3063-3066 3 348 true 10.5281/zenodo.18140176 false
title Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
spellingShingle Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
William Griffiths
Mohsen Ali Asgari
Yuqin Wang
title_short Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
title_full Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
title_fullStr Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
title_full_unstemmed Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
title_sort Current Mass Spectrometry Methods for the Analysis of 7-Ketocholesterol and Related Sterols
author_id_str_mv 3316b1d1b524be1831790933eed1c26e
58bf75dabf1a8c8d58eda61b305d3cfd
c92729b58622f9fdf6a0e7d8f4ce5081
author_id_fullname_str_mv 3316b1d1b524be1831790933eed1c26e_***_William Griffiths
58bf75dabf1a8c8d58eda61b305d3cfd_***_Mohsen Ali Asgari
c92729b58622f9fdf6a0e7d8f4ce5081_***_Yuqin Wang
author William Griffiths
Mohsen Ali Asgari
Yuqin Wang
author2 William Griffiths
Mohsen Ali Asgari
Yuqin Wang
format Journal article
container_title The Journal of Steroid Biochemistry and Molecular Biology
container_start_page 106956
institution Swansea University
issn 0960-0760
doi_str_mv 10.1016/j.jsbmb.2026.106956
publisher Elsevier BV
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Biomedical Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Biomedical Science
url https://doi.org/10.1016/j.jsbmb.2026.106956
document_store_str 0
active_str 0
description In this article we summarise the current mass spectrometry methods used for analysis of 7-ketocholesterol and related sterols, focusing on the advantages of the different methods with emphasis on pre-analytical and analytical precautions to avoid artefactual ex vivo formation of these oxysterols.
published_date 0001-01-01T06:47:20Z
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score 11.096913

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