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Distinct H3K27 Methylation States Drive Cellular Responses to the Histone Demethylase Inhibitor GSK-J4 in Ovarian Cancer Cells
,
Lydia Powell ,
Agne Baseviciene,
David W. James ,
David Howard,
Natalia Sikora,
Jordan Turney,
Neil S. Garton ,
Lavinia Margarit,
Amy Beynon,
Inmaculada Rioja ,
Rab K. Prinjha ,
Nicola R. Harker ,
Deya Gonzalez ,
Steve Conlan ,
Lewis Francis
Molecular Cancer Therapeutics, Pages: OF1 - OF13
Swansea University Authors:
Lydia Powell , Agne Baseviciene, David Howard, Natalia Sikora, Jordan Turney, Lavinia Margarit, Amy Beynon, Deya Gonzalez , Steve Conlan , Lewis Francis
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Author accepted manuscript document released under the terms of a Creative Commons CC-BY licence using the Swansea University Research Publications Policy (rights retention).
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DOI (Published version): 10.1158/1535-7163.mct-25-0268
Abstract
Distinct H3K27 Methylation States Drive Cellular Responses to the Histone Demethylase Inhibitor GSK-J4 in Ovarian Cancer Cells
| Published in: | Molecular Cancer Therapeutics |
|---|---|
| ISSN: | 1535-7163 1538-8514 |
| Published: |
American Association for Cancer Research (AACR)
2026
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa71846 |
| Keywords: |
Histone methylation, H3K27 demethylases, ovarian cancer, GSK-J4, androgen receptor |
|---|---|
| College: |
Faculty of Medicine, Health and Life Sciences |
| Funders: |
The research conducted herein was funded by SMARTExpertise programmes CEAT and RISE via the Welsh Government and the European Regional Development Fund (2017/COL/004; 2017/COL/001), and supported by Genomics Partnership Wales. |
| Start Page: |
OF1 |
| End Page: |
OF13 |