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Bacterial Lipopolysaccharide Induces an Endocrine Switch from Prostaglandin F2  to Prostaglandin E2 in Bovine Endometrium

S Herath, S. T Lilly, D. P Fischer, E. J Williams, H Dobson, C. E Bryant, I. M Sheldon, Martin Sheldon Orcid Logo

Endocrinology, Volume: 150, Issue: 4, Pages: 1912 - 1920

Swansea University Author: Martin Sheldon Orcid Logo

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DOI (Published version): 10.1210/en.2008-1379

Abstract

First work describing the mechanism linking uterine disease to disruption of ovarian luteal function. Surprisingly the switch in prostaglandin secretion was at the phospholipase stage of synthesis.

Published in: Endocrinology
ISSN: 0013-7227
Published: Endocrinology 2009
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URI: https://cronfa.swan.ac.uk/Record/cronfa9970
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Abstract: First work describing the mechanism linking uterine disease to disruption of ovarian luteal function. Surprisingly the switch in prostaglandin secretion was at the phospholipase stage of synthesis.
Item Description: Sheldon designed and led the research; was awarded BBSRC grant funding the research; did some of experiments; did analysis and wrote the paper with Dr Herath (the BBSRC funded postdoc). Substantial contribution to conception & design of study; organisation and conduct of study, and carrying out the study (including acquisition of data); analysis & interpretation of the study data; and drafting the output.
College: Faculty of Medicine, Health and Life Sciences
Issue: 4
Start Page: 1912
End Page: 1920