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The National Infarct Angioplasty Project: UK experience and subsequent developments

Mark de Belder, Peter Ludman, James McLenachan, Clive Weston Orcid Logo, David Cunningham, Emmanouil Lazarides, Huon Gray

Eurointervention, Volume: 10, Pages: T96 - T104

Swansea University Author: Clive Weston Orcid Logo

Abstract

The UK possessed a comprehensive strategy for in-hospital nurse-led thrombolysis for patients with ST-elevation myocardial infarction, and pre-hospital thrombolysis by paramedical ambulance staff. The National Infarct Angioplasty Project was sponsored by the UK government and examined the introducti...

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Published in: Eurointervention
Published: 2014
URI: https://cronfa.swan.ac.uk/Record/cronfa18284
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Abstract: The UK possessed a comprehensive strategy for in-hospital nurse-led thrombolysis for patients with ST-elevation myocardial infarction, and pre-hospital thrombolysis by paramedical ambulance staff. The National Infarct Angioplasty Project was sponsored by the UK government and examined the introduction of primary percutaneous coronary angioplasty (PPCI) in a variety of settings. The project demonstrated that PPCI could be delivered within acceptable timelines, cost-effectively, and to the majority of the population. A decision was therefore made to transform services. There has been a rapid change and by 2012/13 over 95% of eligible patients received PPCI. Survival of patients with STEMI has improved and length of stay in hospital has halved. However, nearly a quarter of STEMI patients do not receive reperfusion therapy (often because of late presentation) and additional work is needed to minimise delays to treatment. There are unexplained differences between regions in numbers of PPCI procedures per million population, and there is also variance between centres in the proportion of patients who are in shock or on a ventilator. Additional research is needed to ensure a consistent approach for these sick patients, who might have the most to gain from early treatment.
Keywords: acute coronary syndrome, myocardial infarction, primary PCI
College: Faculty of Medicine, Health and Life Sciences
Start Page: T96
End Page: T104