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The National Infarct Angioplasty Project: UK experience and subsequent developments

Mark de Belder, Peter Ludman, James McLenachan, Clive Weston Orcid Logo, David Cunningham, Emmanouil Lazarides, Huon Gray

Eurointervention, Volume: 10, Pages: T96 - T104

Swansea University Author: Clive Weston Orcid Logo

Abstract

The UK possessed a comprehensive strategy for in-hospital nurse-led thrombolysis for patients with ST-elevation myocardial infarction, and pre-hospital thrombolysis by paramedical ambulance staff. The National Infarct Angioplasty Project was sponsored by the UK government and examined the introducti...

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Published in: Eurointervention
Published: 2014
URI: https://cronfa.swan.ac.uk/Record/cronfa18284
first_indexed 2014-08-28T01:59:00Z
last_indexed 2018-02-09T04:52:45Z
id cronfa18284
recordtype SURis
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spelling 2014-08-27T22:56:09.6324467 v2 18284 2014-08-27 The National Infarct Angioplasty Project: UK experience and subsequent developments df85e4e0e139d0f46eb683174eba98a9 0000-0002-8995-8199 Clive Weston Clive Weston true false 2014-08-27 MEDS The UK possessed a comprehensive strategy for in-hospital nurse-led thrombolysis for patients with ST-elevation myocardial infarction, and pre-hospital thrombolysis by paramedical ambulance staff. The National Infarct Angioplasty Project was sponsored by the UK government and examined the introduction of primary percutaneous coronary angioplasty (PPCI) in a variety of settings. The project demonstrated that PPCI could be delivered within acceptable timelines, cost-effectively, and to the majority of the population. A decision was therefore made to transform services. There has been a rapid change and by 2012/13 over 95% of eligible patients received PPCI. Survival of patients with STEMI has improved and length of stay in hospital has halved. However, nearly a quarter of STEMI patients do not receive reperfusion therapy (often because of late presentation) and additional work is needed to minimise delays to treatment. There are unexplained differences between regions in numbers of PPCI procedures per million population, and there is also variance between centres in the proportion of patients who are in shock or on a ventilator. Additional research is needed to ensure a consistent approach for these sick patients, who might have the most to gain from early treatment. Journal Article Eurointervention 10 T96 T104 acute coronary syndrome, myocardial infarction, primary PCI 31 8 2014 2014-08-31 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2014-08-27T22:56:09.6324467 2014-08-27T22:36:27.3604867 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Mark de Belder 1 Peter Ludman 2 James McLenachan 3 Clive Weston 0000-0002-8995-8199 4 David Cunningham 5 Emmanouil Lazarides 6 Huon Gray 7
title The National Infarct Angioplasty Project: UK experience and subsequent developments
spellingShingle The National Infarct Angioplasty Project: UK experience and subsequent developments
Clive Weston
title_short The National Infarct Angioplasty Project: UK experience and subsequent developments
title_full The National Infarct Angioplasty Project: UK experience and subsequent developments
title_fullStr The National Infarct Angioplasty Project: UK experience and subsequent developments
title_full_unstemmed The National Infarct Angioplasty Project: UK experience and subsequent developments
title_sort The National Infarct Angioplasty Project: UK experience and subsequent developments
author_id_str_mv df85e4e0e139d0f46eb683174eba98a9
author_id_fullname_str_mv df85e4e0e139d0f46eb683174eba98a9_***_Clive Weston
author Clive Weston
author2 Mark de Belder
Peter Ludman
James McLenachan
Clive Weston
David Cunningham
Emmanouil Lazarides
Huon Gray
format Journal article
container_title Eurointervention
container_volume 10
container_start_page T96
publishDate 2014
institution Swansea University
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description The UK possessed a comprehensive strategy for in-hospital nurse-led thrombolysis for patients with ST-elevation myocardial infarction, and pre-hospital thrombolysis by paramedical ambulance staff. The National Infarct Angioplasty Project was sponsored by the UK government and examined the introduction of primary percutaneous coronary angioplasty (PPCI) in a variety of settings. The project demonstrated that PPCI could be delivered within acceptable timelines, cost-effectively, and to the majority of the population. A decision was therefore made to transform services. There has been a rapid change and by 2012/13 over 95% of eligible patients received PPCI. Survival of patients with STEMI has improved and length of stay in hospital has halved. However, nearly a quarter of STEMI patients do not receive reperfusion therapy (often because of late presentation) and additional work is needed to minimise delays to treatment. There are unexplained differences between regions in numbers of PPCI procedures per million population, and there is also variance between centres in the proportion of patients who are in shock or on a ventilator. Additional research is needed to ensure a consistent approach for these sick patients, who might have the most to gain from early treatment.
published_date 2014-08-31T11:13:37Z
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score 11.088971

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