Journal article 614 views
Clotrimazole as a Potent Agent for Treating the Oomycete Fish Pathogen Saprolegnia parasitica through Inhibition of Sterol 14 -Demethylase (CYP51) / A. G. S. Warrilow; C. M. Hull; N. J. Rolley; J. E. Parker; W. D. Nes; S. N. Smith; D. E. Kelly; S. L. Kelly; Steven Kelly; Diane Kelly; Josie Parker; Claire Hull; Andrew Warrilow
Applied and Environmental Microbiology, Volume: 80, Issue: 19, Pages: 6154 - 6166
Swansea University Authors: Steven, Kelly, Diane, Kelly, Josie, Parker, Claire, Hull, Andrew, Warrilow
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DOI (Published version): 10.1128/AEM.01195-14
Abstract
We have shown that Clotrimazole is an inhibitor of CYP51 in the fish pathogen Saprolegnia parasitica. Our study suggests that it may be used as a preventive treatment against the oomycete infection.
| Published in: | Applied and Environmental Microbiology |
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| Published: |
2014
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa18616 |
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| Abstract: |
We have shown that Clotrimazole is an inhibitor of CYP51 in the fish pathogen Saprolegnia parasitica. Our study suggests that it may be used as a preventive treatment against the oomycete infection. |
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| Keywords: |
CYP51; Saprolegnia parasitica |
| College: |
Swansea University Medical School |
| Issue: |
19 |
| Start Page: |
6154 |
| End Page: |
6166 |