Journal article 789 views
Clotrimazole as a Potent Agent for Treating the Oomycete Fish Pathogen Saprolegnia parasitica through Inhibition of Sterol 14 -Demethylase (CYP51)
Andrew Warrilow,
Claire Hull,
N. J. Rolley,
Josie Parker 
,
W. D. Nes,
S. N. Smith,
Diane Kelly,
Steven Kelly
,
W. D. Nes,
S. N. Smith,
Diane Kelly,
Steven Kelly
Applied and Environmental Microbiology, Volume: 80, Issue: 19, Pages: 6154 - 6166
Swansea University Authors:
Andrew Warrilow, Claire Hull, Josie Parker , Diane Kelly, Steven Kelly
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DOI (Published version): 10.1128/AEM.01195-14
Abstract
We have shown that Clotrimazole is an inhibitor of CYP51 in the fish pathogen Saprolegnia parasitica. Our study suggests that it may be used as a preventive treatment against the oomycete infection.
| Published in: | Applied and Environmental Microbiology |
|---|---|
| Published: |
2014
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa18616 |
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| Abstract: |
We have shown that Clotrimazole is an inhibitor of CYP51 in the fish pathogen Saprolegnia parasitica. Our study suggests that it may be used as a preventive treatment against the oomycete infection. |
|---|---|
| Keywords: |
CYP51; Saprolegnia parasitica |
| College: |
Swansea University Medical School |
| Issue: |
19 |
| Start Page: |
6154 |
| End Page: |
6166 |