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Pre-Surgery Depression and Confidence to Manage Problems Predict Recovery Trajectories of Health and Wellbeing in the First Two Years following Colorectal Cancer: Results from the CREW Cohort Study / C Foster; J Haviland; J Winter; C Grimmett; Seymour Chivers; L Batehup; L Calman; J Corner; A Din; D Fenlon; CM May; A Richardson; PW Smith; of Members
PLOS ONE, Volume: 11, Issue: 5, Start page: e0155434
Swansea University Author: Fenlon, Deborah
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PurposeThis paper identifies predictors of recovery trajectories of quality of life (QoL), health statusand personal wellbeing in the two years following colorectal cancer surgery.Methods872 adults receiving curative intent surgery during November 2010 to March 2012. Questionnairesat baseline, 3, 9,...
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PurposeThis paper identifies predictors of recovery trajectories of quality of life (QoL), health statusand personal wellbeing in the two years following colorectal cancer surgery.Methods872 adults receiving curative intent surgery during November 2010 to March 2012. Questionnairesat baseline, 3, 9, 15, 24 months post-surgery assessed QoL, health status, wellbeing,confidence to manage illness-related problems (self-efficacy), social support, comorbidities,socio-demographic, clinical and treatment characteristics. Group-based trajectoryanalyses identified distinct trajectories and predictors for QoL, health status andwellbeing.ResultsFour recovery trajectories were identified for each outcome. Groups 1 and 2 fared consistentlywell (scores above/within normal range); 70.5%of participants for QoL, 33.3% healthstatus, 77.6%wellbeing. Group 3 had some problems (24.2% QoL, 59.3% health, 18.2%wellbeing); Group 4 fared consistently poorly (5.3% QoL, 7.4% health, 4.2% wellbeing).Higher pre-surgery depression and lower self-efficacy were significantly associated withpoorer trajectories for all three outcomes after adjusting for other important predictorsincluding disease characteristics, stoma, anxiety and social support.
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