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PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised C... / Mikael Fogelholm, Thomas Larsen, Margriet Westerterp-Plantenga, Ian Macdonald, J. Martinez, Nadka Boyadjieva, Sally Poppitt, Wolfgang Schlicht, Gareth Stratton, Jouko Sundvall, Tony Lam, Elli Jalo, Pia Christensen, Mathijs Drummen, Elizabeth Simpson, Santiago Navas-Carretero, Teodora Handjieva-Darlenska, Roslyn Muirhead, Marta Silvestre, Daniela Kahlert, Laura Pastor-Sanz, Jennie Brand-Miller, Anne Raben

Nutrients, Volume: 9, Issue: 6, Start page: 632

Swansea University Author: Gareth Stratton

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DOI (Published version): 10.3390/nu9060632

Abstract

Type-2 diabetes (T2D) is one of the fastest growing chronic diseases worldwide. The PREVIEW project has been initiated to find the most effective lifestyle (diet and physical activity) for the prevention of T2D, in overweight and obese participants with increased risk for T2D. The study is a three-y...

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Published in: Nutrients
ISSN: 2072-6643
Published: 2017
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URI: https://cronfa.swan.ac.uk/Record/cronfa34410
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spelling 2017-08-14T16:06:44.9749370 v2 34410 2017-06-21 PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial 6d62b2ed126961bed81a94a2beba8a01 0000-0001-5618-0803 Gareth Stratton Gareth Stratton true false 2017-06-21 STSC Type-2 diabetes (T2D) is one of the fastest growing chronic diseases worldwide. The PREVIEW project has been initiated to find the most effective lifestyle (diet and physical activity) for the prevention of T2D, in overweight and obese participants with increased risk for T2D. The study is a three-year multi-centre, 2 × 2 factorial, randomised controlled trial. The impact of a high-protein, low-glycaemic index (GI) vs. moderate protein, moderate-GI diet in combination with moderate or high-intensity physical activity on the incidence of T2D and the related clinical end-points are investigated. The intervention started with a two-month weight reduction using a low-calorie diet, followed by a randomised 34-month weight maintenance phase comprising four treatment arms. Eight intervention centres are participating (Denmark, Finland, United Kingdom, The Netherlands, Spain, Bulgaria, Australia, and New Zealand). Data from blood specimens, urine, faeces, questionnaires, diaries, body composition assessments, and accelerometers are collected at months 0, 2, 6, 12, 18, 24, and 36. In total, 2326 adults were recruited. The mean age was 51.6 (SD 11.6) years, 67% were women. PREVIEW is, to date, the largest multinational trial to address the prevention of T2D in pre-diabetic adults through diet and exercise intervention. Participants will complete the final intervention in March, 2018. Journal Article Nutrients 9 6 632 2072-6643 diet; protein; carbohydrate; glycaemic index; physical activity; obesity 31 12 2017 2017-12-31 10.3390/nu9060632 COLLEGE NANME Sport and Exercise Sciences COLLEGE CODE STSC Swansea University 2017-08-14T16:06:44.9749370 2017-06-21T09:16:35.4262239 College of Engineering Engineering Mikael Fogelholm 1 Thomas Larsen 2 Margriet Westerterp-Plantenga 3 Ian Macdonald 4 J. Martinez 5 Nadka Boyadjieva 6 Sally Poppitt 7 Wolfgang Schlicht 8 Gareth Stratton 0000-0001-5618-0803 9 Jouko Sundvall 10 Tony Lam 11 Elli Jalo 12 Pia Christensen 13 Mathijs Drummen 14 Elizabeth Simpson 15 Santiago Navas-Carretero 16 Teodora Handjieva-Darlenska 17 Roslyn Muirhead 18 Marta Silvestre 19 Daniela Kahlert 20 Laura Pastor-Sanz 21 Jennie Brand-Miller 22 Anne Raben 23 0034410-21062017091740.pdf fogelholm2017.pdf 2017-06-21T09:17:40.0900000 Output 977103 application/pdf Version of Record true 2017-06-21T00:00:00.0000000 true eng
title PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
spellingShingle PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
Gareth, Stratton
title_short PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
title_full PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
title_fullStr PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
title_full_unstemmed PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
title_sort PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial
author_id_str_mv 6d62b2ed126961bed81a94a2beba8a01
author_id_fullname_str_mv 6d62b2ed126961bed81a94a2beba8a01_***_Gareth, Stratton
author Gareth, Stratton
author2 Mikael Fogelholm
Thomas Larsen
Margriet Westerterp-Plantenga
Ian Macdonald
J. Martinez
Nadka Boyadjieva
Sally Poppitt
Wolfgang Schlicht
Gareth Stratton
Jouko Sundvall
Tony Lam
Elli Jalo
Pia Christensen
Mathijs Drummen
Elizabeth Simpson
Santiago Navas-Carretero
Teodora Handjieva-Darlenska
Roslyn Muirhead
Marta Silvestre
Daniela Kahlert
Laura Pastor-Sanz
Jennie Brand-Miller
Anne Raben
format Journal article
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container_issue 6
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publishDate 2017
institution Swansea University
issn 2072-6643
doi_str_mv 10.3390/nu9060632
college_str College of Engineering
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description Type-2 diabetes (T2D) is one of the fastest growing chronic diseases worldwide. The PREVIEW project has been initiated to find the most effective lifestyle (diet and physical activity) for the prevention of T2D, in overweight and obese participants with increased risk for T2D. The study is a three-year multi-centre, 2 × 2 factorial, randomised controlled trial. The impact of a high-protein, low-glycaemic index (GI) vs. moderate protein, moderate-GI diet in combination with moderate or high-intensity physical activity on the incidence of T2D and the related clinical end-points are investigated. The intervention started with a two-month weight reduction using a low-calorie diet, followed by a randomised 34-month weight maintenance phase comprising four treatment arms. Eight intervention centres are participating (Denmark, Finland, United Kingdom, The Netherlands, Spain, Bulgaria, Australia, and New Zealand). Data from blood specimens, urine, faeces, questionnaires, diaries, body composition assessments, and accelerometers are collected at months 0, 2, 6, 12, 18, 24, and 36. In total, 2326 adults were recruited. The mean age was 51.6 (SD 11.6) years, 67% were women. PREVIEW is, to date, the largest multinational trial to address the prevention of T2D in pre-diabetic adults through diet and exercise intervention. Participants will complete the final intervention in March, 2018.
published_date 2017-12-31T03:52:28Z
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