Journal article 518 views 97 downloads
Oxysterol research: a brief review
Biochemical Society Transactions, Volume: 47, Issue: 2, Pages: 517 - 526
Swansea University Author: William Griffiths
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DOI (Published version): 10.1042/BST20180135
Abstract
In this article we discuss the recent developments in oxysterol research. Exciting results have been reported relating to the involvement of oxysterols in the fields of neurodegenerative disease, especially in Huntington’s disease, Parkinson’s disease and Alzheimer’s disease; in signalling and devel...
Published in: | Biochemical Society Transactions |
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ISSN: | 0300-5127 1470-8752 |
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Portland Press
2019
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URI: | https://cronfa.swan.ac.uk/Record/cronfa49840 |
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2019-05-24T19:08:30.9635932 v2 49840 2019-04-01 Oxysterol research: a brief review 3316b1d1b524be1831790933eed1c26e 0000-0002-4129-6616 William Griffiths William Griffiths true false 2019-04-01 BMS In this article we discuss the recent developments in oxysterol research. Exciting results have been reported relating to the involvement of oxysterols in the fields of neurodegenerative disease, especially in Huntington’s disease, Parkinson’s disease and Alzheimer’s disease; in signalling and development, in particular in relation to Hedgehog signalling; and in cancer, with special focus on (25R)26-hydroxycholesterol. Methods for the measurement of oxysterols, essential for understanding their mechanism of action in vivo, and valuable for diagnosing rare diseases of cholesterol biosynthesis and metabolism are briefly considered. Journal Article Biochemical Society Transactions 47 2 517 526 Portland Press 0300-5127 1470-8752 31 12 2019 2019-12-31 10.1042/BST20180135 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University UKRI, BB/N015932/1 2019-05-24T19:08:30.9635932 2019-04-01T11:59:03.4579208 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine William Griffiths 0000-0002-4129-6616 1 Yuqin Wang 2 0049840-04042019084822.pdf BST-2018-0135C_VoR.pdf 2019-04-04T08:48:22.1570000 Output 898716 application/pdf Version of Record true 2019-04-04T00:00:00.0000000 Distributed under the terms of a Creative Commons CC-BY 4.0 Licence. true eng |
title |
Oxysterol research: a brief review |
spellingShingle |
Oxysterol research: a brief review William Griffiths |
title_short |
Oxysterol research: a brief review |
title_full |
Oxysterol research: a brief review |
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Oxysterol research: a brief review |
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Oxysterol research: a brief review |
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Oxysterol research: a brief review |
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3316b1d1b524be1831790933eed1c26e |
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3316b1d1b524be1831790933eed1c26e_***_William Griffiths |
author |
William Griffiths |
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William Griffiths Yuqin Wang |
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Biochemical Society Transactions |
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47 |
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517 |
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Swansea University |
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10.1042/BST20180135 |
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Portland Press |
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description |
In this article we discuss the recent developments in oxysterol research. Exciting results have been reported relating to the involvement of oxysterols in the fields of neurodegenerative disease, especially in Huntington’s disease, Parkinson’s disease and Alzheimer’s disease; in signalling and development, in particular in relation to Hedgehog signalling; and in cancer, with special focus on (25R)26-hydroxycholesterol. Methods for the measurement of oxysterols, essential for understanding their mechanism of action in vivo, and valuable for diagnosing rare diseases of cholesterol biosynthesis and metabolism are briefly considered. |
published_date |
2019-12-31T04:01:04Z |
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1763753134112374784 |
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11.016235 |