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Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria

Catrin F. Williams, Christopher George Orcid Logo

Frontiers in Physiology, Volume: 10

Swansea University Author: Christopher George Orcid Logo

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Abstract

The connectedness of signaling components in network structures is a universal featureof biologic information processing. Such organization enables the transduction ofcomplex input stimuli into coherent outputs and is essential in modulating activities asdiverse as the cooperation of bacteria within...

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Published in: Frontiers in Physiology
ISSN: 1664-042X
Published: 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa49863
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first_indexed 2019-04-03T10:14:33Z
last_indexed 2019-09-24T20:12:48Z
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spelling 2019-09-24T13:50:15.5002909 v2 49863 2019-04-02 Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria a2e211f7bd379c81e9c393637803a0a0 0000-0001-9852-1135 Christopher George Christopher George true false 2019-04-02 BMS The connectedness of signaling components in network structures is a universal featureof biologic information processing. Such organization enables the transduction ofcomplex input stimuli into coherent outputs and is essential in modulating activities asdiverse as the cooperation of bacteria within populations and the dynamic organizationof mitochondria within cells. Here, we highlight some common principles that underpincollectivization in bacteria and mitochondrial populations and the advantages conferredby such behavior. We discuss the concept that bacteria and mitochondria act as signaltransducers of their localized metabolic environments to bring about energy-dependentclustering to modulate higher-order function across multiple scales. Journal Article Frontiers in Physiology 10 1664-042X self-organization / mitochondria / collectivization / bacteria / dynamic system 29 3 2019 2019-03-29 10.3389/fphys.2019.00340 https://www.frontiersin.org/articles/10.3389/fphys.2019.00340/full COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University European Union, Wellcome Trust, British Heart Foundation 2019-09-24T13:50:15.5002909 2019-04-02T09:49:27.6472721 Swansea University Medical School Medicine Catrin F. Williams 1 Christopher George 0000-0001-9852-1135 2 0049863-23042019125958.pdf 49863.pdf 2019-04-23T12:59:58.1200000 Output 627460 application/pdf Version of Record true 2019-04-22T00:00:00.0000000 Released under the terms of a Creative Commons Attribution License (CC-BY). true eng
title Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
spellingShingle Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
Christopher George
title_short Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
title_full Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
title_fullStr Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
title_full_unstemmed Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
title_sort Connect and Conquer: Collectivized Behavior of Mitochondria and Bacteria
author_id_str_mv a2e211f7bd379c81e9c393637803a0a0
author_id_fullname_str_mv a2e211f7bd379c81e9c393637803a0a0_***_Christopher George
author Christopher George
author2 Catrin F. Williams
Christopher George
format Journal article
container_title Frontiers in Physiology
container_volume 10
publishDate 2019
institution Swansea University
issn 1664-042X
doi_str_mv 10.3389/fphys.2019.00340
college_str Swansea University Medical School
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hierarchy_top_id swanseauniversitymedicalschool
hierarchy_top_title Swansea University Medical School
hierarchy_parent_id swanseauniversitymedicalschool
hierarchy_parent_title Swansea University Medical School
department_str Medicine{{{_:::_}}}Swansea University Medical School{{{_:::_}}}Medicine
url https://www.frontiersin.org/articles/10.3389/fphys.2019.00340/full
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description The connectedness of signaling components in network structures is a universal featureof biologic information processing. Such organization enables the transduction ofcomplex input stimuli into coherent outputs and is essential in modulating activities asdiverse as the cooperation of bacteria within populations and the dynamic organizationof mitochondria within cells. Here, we highlight some common principles that underpincollectivization in bacteria and mitochondrial populations and the advantages conferredby such behavior. We discuss the concept that bacteria and mitochondria act as signaltransducers of their localized metabolic environments to bring about energy-dependentclustering to modulate higher-order function across multiple scales.
published_date 2019-03-29T04:03:09Z
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