No Cover Image

Journal article 566 views

Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease / Michael Lewis, Joe Annandale, Keir Lewis

Clinical Physiology and Functional Imaging, Volume: 29, Issue: 6, Pages: 431 - 439

Swansea University Authors: Michael Lewis, Keir Lewis

Full text not available from this repository: check for access using links below.

DOI (Published version): 10.1111/j.1475-097X.2009.00891.x

Published in: Clinical Physiology and Functional Imaging
Published: 2009
URI: https://cronfa.swan.ac.uk/Record/cronfa5530
Tags: Add Tag
No Tags, Be the first to tag this record!
Item Description: The novelty of this work was that it was the first to report cardiac benefits of long-term oxygen therapy (LTOT) in chronic obstructive pulmonary disease (COPD), demonstrated here through time-dependent reversal of autonomic nervous system depression. A rigorous pre-post clinical intervention study design and advanced time-series analysis methods provided evidence to support additional cardiac benefits of LTOT. The work led to further clinical collaborations to establish the cardio-pulmonary pathophysiology underlying COPD. This and companion works fostered the knowledge underpinning a major industrial collaboration with Haemair Ltd. (CIRP/A4B grant HE09COL1029) to empirically model a control system for an artificial lung device.
College: College of Engineering
Issue: 6
Start Page: 431
End Page: 439