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Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease / Michael Lewis, Joe Annandale, Keir Lewis

Clinical Physiology and Functional Imaging, Volume: 29, Issue: 6, Pages: 431 - 439

Swansea University Authors: Michael Lewis, Keir Lewis

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DOI (Published version): 10.1111/j.1475-097X.2009.00891.x

Published in: Clinical Physiology and Functional Imaging
Published: 2009
URI: https://cronfa.swan.ac.uk/Record/cronfa5530
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spelling 2016-08-15T09:55:05.6928443 v2 5530 2013-09-03 Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease b59c8f5c056bac7e6995385f22ad1639 Michael Lewis Michael Lewis true false bc53c343c975d6e0ad88c1d8b9ddd70c 0000-0002-8248-6774 Keir Lewis Keir Lewis true false 2013-09-03 EEN Journal Article Clinical Physiology and Functional Imaging 29 6 431 439 31 12 2009 2009-12-31 10.1111/j.1475-097X.2009.00891.x The novelty of this work was that it was the first to report cardiac benefits of long-term oxygen therapy (LTOT) in chronic obstructive pulmonary disease (COPD), demonstrated here through time-dependent reversal of autonomic nervous system depression. A rigorous pre-post clinical intervention study design and advanced time-series analysis methods provided evidence to support additional cardiac benefits of LTOT. The work led to further clinical collaborations to establish the cardio-pulmonary pathophysiology underlying COPD. This and companion works fostered the knowledge underpinning a major industrial collaboration with Haemair Ltd. (CIRP/A4B grant HE09COL1029) to empirically model a control system for an artificial lung device. COLLEGE NANME Engineering COLLEGE CODE EEN Swansea University 2016-08-15T09:55:05.6928443 2013-09-03T06:10:55.0000000 College of Engineering Engineering Michael Lewis 1 Joe Annandale 2 Keir Lewis 0000-0002-8248-6774 3
title Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
spellingShingle Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
Michael, Lewis
Keir, Lewis
title_short Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_full Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_fullStr Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_full_unstemmed Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_sort Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
author_id_str_mv b59c8f5c056bac7e6995385f22ad1639
bc53c343c975d6e0ad88c1d8b9ddd70c
author_id_fullname_str_mv b59c8f5c056bac7e6995385f22ad1639_***_Michael, Lewis
bc53c343c975d6e0ad88c1d8b9ddd70c_***_Keir, Lewis
author Michael, Lewis
Keir, Lewis
author2 Michael Lewis
Joe Annandale
Keir Lewis
format Journal article
container_title Clinical Physiology and Functional Imaging
container_volume 29
container_issue 6
container_start_page 431
publishDate 2009
institution Swansea University
doi_str_mv 10.1111/j.1475-097X.2009.00891.x
college_str College of Engineering
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hierarchy_top_title College of Engineering
hierarchy_parent_id collegeofengineering
hierarchy_parent_title College of Engineering
department_str Engineering{{{_:::_}}}College of Engineering{{{_:::_}}}Engineering
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published_date 2009-12-31T03:15:50Z
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