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3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization

Romeo Romagnoli, Filippo Prencipe, Paola Oliva, Stefania Baraldi, Pier Giovanni Baraldi, Andrea Brancale, Salvatore Ferla Orcid Logo, Ernest Hamel, Roberta Bortolozzi, Giampietro Viola

Bioorganic Chemistry, Volume: 80, Pages: 361 - 374

Swansea University Author: Salvatore Ferla Orcid Logo

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Published in: Bioorganic Chemistry
ISSN: 0045-2068
Published: Elsevier BV 2018
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Keywords: Microtubule targeting-agent; Structure-activity relationship; Tubulin polymerization; Antiproliferative activity; Molecular docking
College: Faculty of Medicine, Health and Life Sciences
Start Page: 361
End Page: 374