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A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents

Romeo Romagnoli, Paola Oliva, Maria Kimatrai Salvador, Stefano Manfredini, Chiara Padroni, Andrea Brancale, Salvatore Ferla Orcid Logo, Ernest Hamel, Roberto Ronca, Federica Maccarinelli, Fatlum Rruga, Elena Mariotto, Giampietro Viola, Roberta Bortolozzi

European Journal of Medicinal Chemistry, Volume: 214, Start page: 113229

Swansea University Author: Salvatore Ferla Orcid Logo

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Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2021
Online Access: Check full text

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Keywords: Antimitotic agents; Structure-activity relationship; 1H-pyrrole; Antiproliferative activity; Tubulin polymerization
College: Faculty of Medicine, Health and Life Sciences
Start Page: 113229