Journal article 806 views 111 downloads
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
Romeo Romagnoli,
Paola Oliva,
Maria Kimatrai Salvador,
Stefano Manfredini,
Chiara Padroni,
Andrea Brancale,
Salvatore Ferla
,
Ernest Hamel,
Roberto Ronca,
Federica Maccarinelli,
Fatlum Rruga,
Elena Mariotto,
Giampietro Viola,
Roberta Bortolozzi
European Journal of Medicinal Chemistry, Volume: 214, Start page: 113229
Swansea University Author:
Salvatore Ferla
-
PDF | Accepted Manuscript
©2021 All rights reserved. All article content, except where otherwise noted, is licensed under a Creative Commons Attribution Non-Commercial No Derivatives License (CC-BY-NC-ND)
Download (7.24MB)
DOI (Published version): 10.1016/j.ejmech.2021.113229
Abstract
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
Published in: | European Journal of Medicinal Chemistry |
---|---|
ISSN: | 0223-5234 |
Published: |
Elsevier BV
2021
|
Online Access: |
Check full text
|
URI: | https://cronfa.swan.ac.uk/Record/cronfa56244 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Keywords: |
Antimitotic agents; Structure-activity relationship; 1H-pyrrole; Antiproliferative activity; Tubulin polymerization |
---|---|
College: |
Faculty of Medicine, Health and Life Sciences |
Start Page: |
113229 |