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A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
Romeo Romagnoli,
Paola Oliva,
Maria Kimatrai Salvador,
Stefano Manfredini,
Chiara Padroni,
Andrea Brancale,
Salvatore Ferla
,
Ernest Hamel,
Roberto Ronca,
Federica Maccarinelli,
Fatlum Rruga,
Elena Mariotto,
Giampietro Viola,
Roberta Bortolozzi
European Journal of Medicinal Chemistry, Volume: 214, Start page: 113229
Swansea University Author:
Salvatore Ferla
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DOI (Published version): 10.1016/j.ejmech.2021.113229
Abstract
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
Published in: | European Journal of Medicinal Chemistry |
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ISSN: | 0223-5234 |
Published: |
Elsevier BV
2021
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Online Access: |
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URI: | https://cronfa.swan.ac.uk/Record/cronfa56244 |
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Keywords: |
Antimitotic agents; Structure-activity relationship; 1H-pyrrole; Antiproliferative activity; Tubulin polymerization |
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College: |
Faculty of Medicine, Health and Life Sciences |
Start Page: |
113229 |