Journal article 240 views 24 downloads
LIPID MAPS: update to databases and tools for the lipidomics community
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Robert M Andrews ,
Simon Andrews ,
Lauren Cockayne,
Edward A Dennis ,
Eoin Fahy ,
Caroline Gaud ,
William Griffiths ,
Geoff Jukes,
Maksim Kolchin ,
Karla Mendivelso,
Andrea F Lopez-Clavijo ,
Caroline Ready,
Shankar Subramaniam,
Valerie B O’Donnell
Nucleic Acids Research
Swansea University Author:
William Griffiths
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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research. Distributed under the terms of a Creative Commons Attribution 4.0 International License (CC BY 4.0).
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DOI (Published version): 10.1093/nar/gkad896
Abstract
LIPID MAPS (LIPID Metabolites and Pathways Strategy), www.lipidmaps.org , provides a systematic and standardized approach to organizing lipid structural and biochemical data. Founded 20 years ago, the LIPID MAPS nomenclature and classification has become the accepted community standard. LIPID MAPS p...
| Published in: | Nucleic Acids Research |
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| ISSN: | 0305-1048 1362-4962 |
| Published: |
Oxford University Press (OUP)
2023
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa64901 |
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| Abstract: |
LIPID MAPS (LIPID Metabolites and Pathways Strategy), www.lipidmaps.org , provides a systematic and standardized approach to organizing lipid structural and biochemical data. Founded 20 years ago, the LIPID MAPS nomenclature and classification has become the accepted community standard. LIPID MAPS provides data bases for cataloging and identifying lipids at varying levels of characterization in addition to numerous software tools and educational resources, and became an ELIXIR-UK data resource in 2020. This paper describes the expansion of existing databases in LIPID MAPS, including richer metadata with literature provenance, taxonomic data and improved interoperability to facilitate FAIR compliance. A joint project funded by ELIXIR-UK, in collaboration with WikiPathways, curates and hosts pathway data, and annotates lipids in the context of their biochemical pathways. Updated features of the search infrastructure are described along with implementation of programmatic access via API and SPARQL. New lipid-specific databases have been developed and provision of lipidomics tools to the community has been updated. Training and engagement have been expanded with webinars, podcasts and an online training school. |
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| Keywords: |
LIPID MAPS, databases, metadata, lipid structural data, lipid biochemical data |
| College: |
Faculty of Medicine, Health and Life Sciences |
| Funders: |
Wellcome Trust [203014/Z/16/Z]; National Institutes of Health [U2CDK119886]; EAD is supported by National Institutes of Health NIGMS MIRA [R35 GM139641]. We gratefully acknowledge unrestricted sponsorship to LIPID MAPS from Cayman Chemical, Merck and Avanti Polar Lipids. Funding for open access charge: Cardiff University via the OUP Full Collection Read and Publish Agreement 2021-2023. |