Journal article 237 views
Expanding the genome information on Bacillales for biosynthetic gene cluster discovery
Lijie Song,
Lasse Johan Dyrbye Nielsen,
Xinming Xu,
Omkar Satyavan Mohite,
Matin Nuhamunada 
,
Zhihui Xu,
Rob Murphy,
Kasun Bodawatta,
Michael Poulsen ,
Mohamed Hatha Abdulla,
Eva C. Sonnenschein ,
Tilmann Weber ,
Ákos T. Kovács
,
Zhihui Xu,
Rob Murphy,
Kasun Bodawatta,
Michael Poulsen ,
Mohamed Hatha Abdulla,
Eva C. Sonnenschein ,
Tilmann Weber ,
Ákos T. Kovács
Scientific Data, Volume: 11, Start page: 1267
Swansea University Author:
Eva C. Sonnenschein
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1038/s41597-024-04118-x
Abstract
This study showcases 121 new genomes of spore-forming Bacillales from strains collected globally from a variety of habitats, assembled using Oxford Nanopore long-read and MGI short-read sequences. Bacilli are renowned for their capacity to produce diverse secondary metabolites with use in agricultur...
| Published in: | Scientific Data |
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| ISSN: | 2052-4463 |
| Published: |
Springer Nature
2024
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa66577 |
| Abstract: |
This study showcases 121 new genomes of spore-forming Bacillales from strains collected globally from a variety of habitats, assembled using Oxford Nanopore long-read and MGI short-read sequences. Bacilli are renowned for their capacity to produce diverse secondary metabolites with use in agriculture, biotechnology, and medicine. These secondary metabolites are encoded within biosynthetic gene clusters (smBGCs). smBGCs have significant research interest due to their potential as sources of new bioactivate compounds. Our dataset includes 62 complete genomes, 2 at chromosome level, and 57 at contig level, covering a genomic size range from 3.50 Mb to 7.15 Mb. Phylotaxonomic analysis revealed that these genomes span 16 genera, with 69 of them belonging to Bacillus. A total of 1,176 predicted BGCs were identified by in silico genome mining. We anticipate that the open-access data presented here will expand the reported genomic information of spore-forming Bacillales and facilitate a deeper understanding of the genetic basis of Bacillales’ potential for secondary metabolite production. |
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| Item Description: |
Data Descriptor |
| College: |
Faculty of Science and Engineering |
| Funders: |
This project was supported by the Danish National Research Foundation (DNRF137) for the Center for Microbial Secondary Metabolites, and Novo Nordisk Foundation within the INTERACT project of the Collaborative Crop Resiliency Program (NNF19SA0059360). TW acknowledges funding from the Novo Nordisk Foundation (NNF20CC0035580). |
| Start Page: |
1267 |